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Volume 608 Issue 7924, 25 August 2022

Porous water

Many gases can be dissolved in water, but the amount of gas that can be held by the liquid is relatively low. In this week’s issue, Jarad Mason and his colleagues present a system that creates permanently ‘porous’ water, allowing gases to be stored at high concentrations within the liquid. To achieve this, the researchers suspended tailored microporous nanocrystals in water and other aqueous solutions. The internal surfaces of the solids repel water molecules, thereby creating ‘dry’ pores that can readily adsorb gases from the surrounding liquid. This allowed the team to store gases, including oxygen and carbon dioxide, at much higher concentrations than is possible in water alone. The work could have implications in energy and biomedicine, because highly oxygenated water might be able to act as a solvent for electrocatalysis or a substitute for blood.

Cover image: Younghee Lee

This Week

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  • News & Views

    • Precise optical experiments reveal that quantum excitations in semiconductors share similarities with a host of growing interfaces. The parallels inspire a fresh approach to studying the dynamics of diverse systems in a controllable way.

      • Sebastian Diehl
      News & Views
    • In 1987, two independent groups cloned a gene that encoded the potassium-ion-channel protein Shaker, enabling functional and structural studies that have transformed ion-channel research.

      • Crina M. Nimigean
      News & Views
    • Porous solids have been dispersed in water to produce suspensions that can carry much more oxygen than blood can. Such ‘porous water’ opens the way to water-based formulations for biomedical use.

      • Margarida Costa Gomes
      News & Views
    • The identity of the enzyme that enables vitamin K to combat the adverse side effects of a drug called warfarin has been long sought. Analysis of a type of cell death called ferroptosis has now unexpectedly solved the mystery.

      • Nathan P. Ward
      • Gina M. DeNicola
      News & Views
    • A close look at the cells that drive cancer growth after chemotherapy, and thereby contribute to fatal tumour progression, provides new insights into the identity of the cells that manage to survive treatment.

      • Sumaiyah K. Rehman
      • Catherine A. O’Brien
      News & Views
  • Articles

    • By using three silicon spin qubits to construct a phase-correcting code, quantum error correction is implemented and protection of the three-qubit state against any phase-flip error on one of the three qubits is demonstrated.

      • Kenta Takeda
      • Akito Noiri
      • Seigo Tarucha
      Article Open Access
    • Experiments show that the dynamics of phase fluctuations  in a one-dimensional polariton condensate falls in the Kardar–Parisi–Zhang universality class, and theoretical analysis supports this finding revealing the key signatures of this universality class.

      • Quentin Fontaine
      • Davide Squizzato
      • Jacqueline Bloch
    • A mechanical integrated circuit material based on Boolean mathematics and reconfigurable electrical circuits is created to demonstrate scalable information processing in synthetic, engineered soft matter.

      • Charles El Helou
      • Benjamin Grossmann
      • Ryan L. Harne
    • Modification of the internal and external surface chemistry of microporous zeolite and metal–organic framework nanocrystals leads to a generalizable strategy to aqueous porous liquids and impart high gas-carrying capacities to liquid water.

      • Daniel P. Erdosy
      • Malia B. Wenny
      • Jarad A. Mason
    • An integrated ozone depletion metric indicates the impact of any new emission and provides a useful complementary metric of the impact of specific emissions of an ozone depleting substance for both the scientific and policy communities.

      • John A. Pyle
      • James Keeble
      • Paul T. Griffiths
    • Sequencing of individual human lymphocyte clones shows that they are highly prone to mutations, with higher burdens in memory cells than in naive cells arising from mutational processes associated with differentiation and tissue residency.

      • Heather E. Machado
      • Emily Mitchell
      • Peter J. Campbell
      Article Open Access
    • Live-seq, a single-cell transcriptome profiling approach that preserves cell viability during RNA extraction using fluidic force microscopy, can address a range of biological questions by transforming scRNA-seq from an end-point to a temporal analysis approach.

      • Wanze Chen
      • Orane Guillaume-Gentil
      • Bart Deplancke
      Article Open Access
    • A time-resolved high-resolution map of human cardiac remodelling after myocardial infarction, integrating single-cell transcriptomic, chromatin accessibility and spatial transcriptomic data, provides a valuable resource for the field.

      • Christoph Kuppe
      • Ricardo O. Ramirez Flores
      • Rafael Kramann
    • Biochemical and lipidomic analyses identify an anti-ferroptotic function of vitamin K and reveal ferroptosis suppressor protein 1 (FSP1) as the enzyme mediating warfarin-resistant vitamin K reduction in the canonical vitamin K cycle.

      • Eikan Mishima
      • Junya Ito
      • Marcus Conrad
      Article Open Access
    • A genetic lineage-tracing system in human colorectal organoids identifies a population of dormant cancer cells that persists during chemotherapy and enables cancer regrowth, and the cell-adhesion molecule COL17A1 has a key role in the process of breaking dormancy.

      • Yuki Ohta
      • Masayuki Fujii
      • Toshiro Sato
    •  Malignant evolution enabled by p53 inactivation in mice proceeds through an ordered and predictable pattern of Trp53 loss of heterozygosity, accumulation of deletions, genome doubling and the emergence of gains and amplifications.

      • Timour Baslan
      • John P. Morris IV
      • Scott W. Lowe
      Article Open Access
    • Through structural analysis of the activation of bacterial STING, the molecular basis of STING filament formation and TIR effector domain activation in antiphage signalling is defined.

      • Benjamin R. Morehouse
      • Matthew C. J. Yip
      • Philip J. Kranzusch
      Article Open Access
    • A bacterial antiviral defence system generates a cyclic tri-adenylate that binds to a TIR–SAVED effector, inducing formation of a superhelical structure with adjacent TIR domains organizing into an active site, allowing NAD+ degradation.

      • Gaëlle Hogrel
      • Abbie Guild
      • Malcolm F. White
    • The Polα–primase-associated CST complex organizes telomeric C-strand DNA synthesis, and, in combination with telomerase, it carries out complete replication of the single-stranded DNA overhang found at human telomeres.

      • Arthur J. Zaug
      • Karen J. Goodrich
      • Thomas R. Cech
      Article Open Access
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Nature Outlook

  • Depression afflicts roughly one in 25 people worldwide.

    Nature Outlook
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