Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Volume 576 Issue 7785, 5 December 2019

Genomes from Asia

To date, human genetic studies have focused largely on Europeans, which has limited the diversity of individuals represented in the genetic data sets. With a plan to sequence and analyse the genomes of 100,000 Asian individuals, the GenomeAsia 100K project aims to play a major part in plugging that gap. In this week’s issue, the consortium presents the data from the pilot phase of the project: a whole-genome reference data set from 1,739 individuals of 219 population groups and 64 countries across Asia. The researchers use the data to catalogue genetic variation, population structure and disease associations. They also find that Asia has sizeable founder populations, where groups have broken away from the original population to form a new one, and suggest further study of these could help identify genes associated with rare diseases.

Cover image: Allison Bruce, Eric Stawiski and Hie Lim Kim

This Week

News in Focus

Books & Arts




Amendments & Corrections

Innovations In

  • Innovations In |

    The DNA drug revolution

    Physicians have long been unable to touch the biological code that drives disease.

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing


Quick links