Governments must take heed of latest IPCC assessment
Report makes clear that there is no safe level of global warming.
Report makes clear that there is no safe level of global warming.
Treatments tailored to individuals rely on the wisdom of crowds.
The bodies that govern the Nobel prizes have much to do when it comes to increasing diversity among laureates.
Women in science still don’t get what they deserve, explains Virginia Valian, 20 years on from her landmark book on bias.
Interspecies mating helps to protect Homo sapiens against viruses.
A lightning-fast burst of current prods an alloy into a superconducting state.
Automated system takes only 80 hours to turn out hundreds of doses of a medical product made by living organisms.
Mountains in South Africa’s Barberton region contain a rare hoard of minerals more than 3 billion years old.
Microbes may have switched from reliance on sunshine to consuming hydrogen.
Samples from ancient latrines pinpoint the squirming parasites that infested residents’ guts.
Plant cells pressed into service as swift and biodegradable couriers.
The week in science: 5–11 October 2018.
One of the two leading candidates has proposed pulling the country out of the Paris climate agreement while the other would seek to boost research funding.
Humanity has a limited window in which it can hope to avoid the worst effects of climate change, according to climate report.
Advocates of homeopathy say that the rat study is evidence of the practice’s efficacy, but some scientists have cast doubt on the paper.
Robert-Jan Smits takes Plan S to the White House to seek support from US funders and policymakers.
The death penalty, uranium mining and the endangered dusky gopher frog are among the topics that justices will consider this year.
Frances Arnold, Gregory Winter and George Smith controlled evolution in the lab to produce greener technologies and new medicines.
Miniature instruments could help the European Union determine whether nations are meeting pledges to cut greenhouse-gas emissions.
The race is on to build up wetlands barriers in one of North America’s largest estuaries.
Polygenic risk scores represent a giant leap for gene-based diagnostic tests. Here’s why they’re still so controversial.
Sand-grain-sized computers, self-healing materials and constellations of craft would reboot our reach, explain Igor Levchenko, Michael Keidar and colleagues.
Alexander Klimburg lauds a study on the impact of the Russian disinformation campaign.
Rob Latham savours the tumultuous tale of four men who reshaped the genre.
Beth Fowkes Tobin applauds a book on Martin Lister and his brilliant daughters Anna and Susanna.
DNA sequencing is helping clinicians to unravel the underpinnings of disease in individual patients.
Researchers who enjoy globe-trotting may find satisfaction in helping tourists and travellers to connect with science.
I was lucky to have a PhD supervisor whose mentorship transformed my academic experience, says Emma Kathryn White.
UK Biobank contains a wealth of data on genetics, health and more from 500,000 participants. A detailed overview of the biobank and an analysis of its brain-imaging data show the value of this resource.
Contrary to previous assumptions, it seems the cells that line blood vessels are derived from more than one source. In addition to their known developmental path, they can arise from progenitors of embryonic blood cells.
Light-emitting diodes made from perovskite semiconductors have reached a milestone in the efficiency with which they emit light — potentially ushering in a new platform for lighting and display technology.
The movements of relocated wild animals reveal that a lost migratory skill was regained over successive generations. This suggests that skill improvements can occur over time as animals learn expertise from each other.
Experiments reveal a previously unreported type of electronic noise that is caused by temperature gradients. The finding has practical implications, and could help in detecting unwanted hotspots in electrical circuits.
Gene editing has now been used to introduce every possible single-nucleotide mutation into key protein-coding regions in the cancer-predisposition gene BRCA1, to identify the variants that are linked to cancer risk.
Deep phenotype and genome-wide genetic data from 500,000 individuals from the UK Biobank, describing population structure and relatedness in the cohort, and imputation to increase the number of testable variants to 96 million.
Genome-wide association studies of brain imaging data from 8,428 individuals in UK Biobank show that many of the 3,144 traits studied are heritable, and genes associated with individual phenotypes are identified.
Germline BRCA1 loss-of-function variants are associated with predisposition to early-onset breast and ovarian cancer; here the authors use CRISPR/Cas9 genome editing to functionally assess thousands of BRCA1 variants in order to facilitate the clinical interpretation of these variants.
New blood vessel endothelial cells arise from differentiation of erythro-myeloid progenitor cells to complement the proliferation of pre-existing endothelial cells.
Lyman-α emission from atomic hydrogen shows the location of warm gas and is ubiquitous around galaxies between redshifts of 3 and 6, thereby covering nearly all the sky.
Observations of a jet from a strongly magnetized neutron star reveal that strong magnetic fields do not prevent jet formation and suggest that stellar properties influence jet power.
A reinforcement learning approach allows a suitably equipped glider to navigate thermal plumes autonomously in an open field.
A fundamental electronic noise—beyond electronic thermal noise and voltage-activated shot noise—that is generated by temperature differences across nanoscale conductors is demonstrated, with possible implications for thermometry and electronics.
A strategy for managing the compositional distribution in metal halide perovskite light-emitting diodes enables them to surpass 20% external quantum efficiency—a step towards their practical application in lighting and displays.
The formation of submicrometre-scale structure in perovskite light-emitting diodes can raise their external quantum efficiency beyond 20%, suggesting the possibility of both high efficiency and high brightness.
By intercalating large ammonium molecules to exfoliate MoS2 with preservation of the 2H-phase, highly uniform solutionprocessable 2D semiconductor nanosheets are obtained for the scalable fabrication of large-area thin-film electronics.
Simulations of commonly proposed forest-management portfolios for Europe show that no single portfolio would meet all the requirements of the Paris Agreement, and climate benefits from forest management would be modest and local.
Low soil moisture may reduce, or even reverse, the potential benefits of climate warming on photosynthesis in mesic, seasonally cold environments, both during drought and in regularly occurring, modestly dry periods during the growing season.
A genome-wide association study of approximately 7,000 patients with neurodevelopmental disorders demonstrates that overall risk and clinical presentation in putative monogenic disorders is also influenced by common genetic variants present in the general population.
Cultures grown from small aggregates of mouse embryonic stem cells can be induced to organize spatial and temporal patterns of gene expression that parallel those of the early embryo, offering a potentially useful system for studying early development.
In the CRISPR type III system, ‘ring’ nucleases possess a metal-independent mechanism that cleaves cyclic oligoadenylate ring molecules to switch off the antiviral state in cells.
Single-cell micrococcal nuclease sequencing simultaneously measures chromatin accessibility and genome-wide nucleosome positioning in single cells to reveal principles of nucleosome organization.
Crystal structures of DltB, a bacterial membrane-bound O-acyltransferase, are reported both alone and in complex with the d-alanyl donor protein DltC.
An alternative Japan experience Meet the sides of Japanese cities that most international researchers never see