Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Volume 539 Issue 7628, 10 November 2016

Artistic representation of interconnected neurons at cellular resolution. With neuronal regeneration being extremely limited in the adult mammalian neocortex, one possible strategy to drive repair in the brain following injury is to utilize transplanted embryonic neurons. However, it is not known how well these neurons develop and integrate into established circuits in the adult. A study published in this issue of Nature uses two-photon microscopy and monosynaptic tracing to show that embryonic neurons transplanted into the visual cortex of adult mice can mature and achieve adult-like properties within four to eight weeks, receiving appropriate inputs and establishing sensory stimulus selective responses. Cover art by Ara Hacobian.

Editorial

Top of page ⤴

World View

  • We must start an ambitious and professional global programme to explore and preserve invertebrate biodiversity, says Axel Hochkirch.

    • Axel Hochkirch
    World View
Top of page ⤴

Research Highlights

Top of page ⤴

Seven Days

Top of page ⤴

News

Top of page ⤴

News Feature

  • Three things are needed to turn the tide on the costliest crisis in health care.

    • Elie Dolgin
    News Feature
Top of page ⤴

Comment

  • Focused grass-roots collaborations that start small and scale up could overcome technical and sociological barriers to 'big' neuroscience, argue Zachary F. Mainen, Michael Häusser and Alexandre Pouget.

    • Zachary F. Mainen
    • Michael Häusser
    • Alexandre Pouget
    Comment
  • The IPCC should supply policymakers with realistic regional projections of how the seas will respond to warming, write Daniela Schmidt and Philip W. Boyd.

    • Daniela Schmidt
    • Philip W. Boyd
    Comment
Top of page ⤴

Books & Arts

  • Michael Heneka applauds a sweeping survey of dementia that explores research, diagnosis and care.

    • Michael Heneka
    Books & Arts
  • Barbara Kiser reviews five of the week's best science picks.

    • Barbara Kiser
    Books & Arts
Top of page ⤴

Correspondence

Top of page ⤴

News & Views

  • A nanoscale imaging method that uses ultrashort light pulses to initiate and follow the motion of a single molecule adsorbed on a solid surface opens a window onto the physical and chemical dynamics of molecules on surfaces. See Letter p.263

    • Nicholas Camillone III
    News & Views
  • In many mammals, the gene Ostn is expressed in muscles and bones. The discovery that the primate OSTN gene has been repurposed to also act in neurons provides clues to how humans evolved their cognitive abilities. See Article p.242

    • Justine Kupferman
    • Franck Polleux
    News & Views
  • Expression of a blood-cancer-associated genetic mutation in the non-blood cells of the bone marrow is sufficient to cause blood cancer in mice. This finding could point to new approaches to treating an often-fatal disease. See Letter p.304

    • Gordon Chan
    • Benjamin G. Neel
    News & Views
  • The discovery in 1936 that rats respond to various damaging stimuli with a general response that involves alarm, resistance and exhaustion launched the discipline of stress research.

    • George Fink
    News & Views
  • Interactions between the magnetic dipoles of dysprosium atoms in an ultracold gas can produce a 'self-bound' droplet. This provides a useful isolated system for probing the quantum-mechanical properties of ultracold gases. See Letter p.259

    • Bruno Laburthe-Tolra
    News & Views
  • Two monkeys subjected to a spinal-cord injury that paralysed one leg have regained the ability to walk, thanks to technology that re-establishes communication between the brain and spinal cord. See Letter p.284

    • Andrew Jackson
    News & Views
Top of page ⤴

Introduction

Top of page ⤴

Review Article

Top of page ⤴

Article

Top of page ⤴

Letter

Top of page ⤴

Erratum

Top of page ⤴

Corrigendum

Top of page ⤴

Technology Feature

Top of page ⤴

Correction

Top of page ⤴

Feature

Top of page ⤴

Career Brief

Top of page ⤴

Futures

  • Lost time.

    • Troy Stieglitz
    Futures
Top of page ⤴
Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing

Search

Quick links