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Volume 474 Issue 7352, 23 June 2011

By 2050, two-thirds of the world's population will be living in cities. Although city living has many advantages, rapidly increasing urbanization has major health implications — schizophrenia is more common in people born in cities than in those from less heavily populated districts, and living in cities increases the rates of depression and anxiety disorders. It has been suggested that social stress plays a part in these effects, but the mechanisms involved are unknown. Now, in a study of healthy German volunteers using functional magnetic resonance imaging, a key brain structure for negative emotion (the amygdala) was found to be more active during stress in city dwellers, and a regulatory brain area (the cingulate cortex) more active in people born in cities. These results identify potential mechanisms linking social environment and mental illness, and might contribute to planning healthier urban surroundings. Cover image: O. Dusegård/Getty.

Postdoc Journal

Editorial

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    A quantitative approach to the humanities enriches research.

World View

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Research Highlights

Seven Days

News

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Correction

News Feature

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Comment

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Books & Arts

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    • Alison Abbott

Correspondence

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    Many of us were raised or currently live in an urban environment. A neuroimaging study now reveals how this affects brain function when an individual is faced with a stressful situation. See Letter p.498

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    Special:

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    • Adán Cabello
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Article

Letter

Feature

Column

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Futures

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Outlook

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  • Outlook |

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  • Outlook |

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    • Neil Savage
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    • Jeremy Martin
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    • Natasha Gilbert
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    • Lee R. Lynd
    • Jeremy Woods
  • Outlook |

    Biofuels have been hailed as key to reducing our fossil-fuel dependence, yet their environmental and social impacts remain uncertain. A complex task lies ahead for policy makers.

    • Martin Robbins
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    • Marcia Moraes

Nature Outlook

  • Nature Outlook |

    Biofuels

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