Space is not completely empty; the vacuum teems with quantum mechanical energy fluctuations able to generate an attractive force between objects that are very close to each other. This Casimir Lifshitz force can cause static friction or stiction in nanomachines, which must be strongly reduced. Until now only attractive interactions have been reported but in theory, if vacuum is replaced by certain media, Casimir-Lifshitz forces should become repulsive. This has now been confirmed experimentally. Repulsion, weaker than the attractive force, was measured in a carefully chosen system of interacting materials immersed in fluid. The magnitude of both forces increases as separation decreases. The repulsive forces could conceivably allow quantum levitation of objects in a fluid and lead to new types of switchable nanoscale devices with ultra-low static friction. Levitation depends only on the dielectric properties of the various materials. The cover illustrates repulsion between a tiny gold sphere and a silica substrate (left). Replace the silica with gold (right), and the force becomes attractive.