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Volume 439 Issue 7076, 2 February 2006

Editorial

  • Unfounded public fears place pressures on vaccine developers that go beyond reasonable safety considerations, as the search for an acceptable vaccine against Lyme disease may demonstrate.

    Editorial

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  • The reprocessing of nuclear fuel is an idea that should be laid to rest.

    Editorial
  • Progress in addressing Africa's largest health problem remains painfully slow.

    Editorial
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Research Highlights

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News

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News in Brief

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Correction

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News Feature

  • The first vaccine against Lyme disease was withdrawn because patients distrusted it. Should market forces be allowed to shape the next one, asks Alison Abbott.

    • Alison Abbott
    News Feature
  • Two decades after plans were set in motion for the world's most powerful ground-based telescope, astronomers are bracing themselves for a downgrade to curb escalating costs. Jeff Kanipe reports.

    • Jeff Kanipe
    News Feature
  • A horrible facial cancer is decimating the Tasmanian devil population. But researchers in Australia think they have found a way to save the species. Carina Dennis reports.

    • Carina Dennis
    News Feature
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Business

  • Probing parasite’s evasive tricks could herald novel anti-inflammatory compounds.

    • Colin Macilwain
    Business
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Correspondence

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Books & Arts

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Essay

  • When James Watson and Francis Crick unveiled their structure of DNA, one of the two kinds of base pair in the molecule was given two hydrogen bonds instead of three. Who spotted the third bond and when?

    • Simon Wain-Hobson
    Essay
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News & Views

  • Further observations of an object dubbed 2003 UB313, which lies beyond Neptune, show that its diameter is around 3,100 kilometres. This makes it larger than Pluto, the smallest ‘traditional’ Solar System planet.

    • Scott S. Sheppard
    News & Views
  • DNA is duplicated within a complex macromolecular machine. Insights into how replication begins and how this is coordinated with progression of DNA synthesis come from a diverse range of sources.

    • Stephen D. Bell
    News & Views
  • Self-organization of soft-matter components can create complex and beautiful structures. But the intricate structures created by adding a second stage of organization could reveal more than just a pretty face.

    • Alfons van Blaaderen
    News & Views
  • Despite its tiny size, the fruitfly brain is staggeringly intricate. So teasing apart how it remembers things — even a simple line pattern — is a daunting task. Progress is being made, thanks to genetic innovations.

    • William G. Quinn
    News & Views
  • Designing efficient solid-state catalysts would be easier if we knew which parts of them do what. Fluorescence microscopy could help: the technique allows single catalytic events to be observed in real time.

    • Bert M. Weckhuysen
    News & Views
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Brief Communication

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Article

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Letter

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Prospects

  • Universities take a look at postdocs' mental-health issues

    • Paul Smaglik
    Prospects
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Movers

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Recruiters and Industry

  • Professional organization helps women scientists move from bench to board room.

    • Robbie Melton
    Recruiters and Industry
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Alumnus Journal

  • A watershed year for a former Graduate Journal writer brings fresh career opportunities.

    • Amber Jenkins
    Alumnus Journal
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Futures

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Authors

  • How climate data are helping to predict malaria outbreaks in Africa.

    Authors
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