Reviews & Analysis

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  • A 3D-printing technique has been developed that can produce millimetre- to centimetre-scale objects with micrometre-scale features. It relies on chemical reactions triggered by the intersection of two light beams.

    • Cameron Darkes-Burkey
    • Robert F. Shepherd
    News & Views
  • Oscillations in neuronal activity in the medial temporal lobe of the human brain encode proximity to boundaries such as walls, both when navigating while walking and when watching another person do so.

    • Hugo J. Spiers
    News & Views
  • Pain-sensing nerve cells can mobilize blood stem cells in mice, with a component of chilli peppers being one stimulus. The finding holds the promise of improving procedures for stem-cell transplantation.

    • Anastasia N. Tikhonova
    • Iannis Aifantis
    News & Views
  • A high-throughput technique has been developed to screen genes implicated in neurodevelopmental diseases in 3D cell cultures. It reveals a mechanism that might be involved in a rare disorder called microcephaly.

    • Adriana Cherskov
    • Nenad Sestan
    News & Views
  • Most SARS-CoV-2 infections are undocumented. French health-care records and modelling were used to assess the rate of documentation of COVID-19 cases. The findings highlight the need for improved identification of infections.

    • Jeffrey Shaman
    News & Views
  • Wetlands remove nitrate pollution from water effectively. An analysis shows that this effect is constrained in the United States by the distribution of wetlands, and could be increased by targeting wetland restoration to nitrate sources.

    • Jacques C. Finlay
    News & Views
  • Atomic clocks known as optical clocks are more accurate and stable than current timekeepers. Two quantum-engineering approaches could improve the performance of optical clocks even further and extend their applications.

    • Christian Lisdat
    • Carsten Klempt
    News & Views
  • An analysis of more than 6 million YouTube videos finds that people around the world make similar facial expressions in similar social contexts. The study brings data science to the debate about the universality of emotion categories.

    • Lisa Feldman Barrett
    News & Views
  • Precise maps of routine first-dose measles vaccinations show slowing progress around the world between 2010 and 2019, and large gaps in coverage in many places. Many countries are unlikely to achieve global 2020 coverage targets.

    • C. Edson Utazi
    • Andrew J. Tatem
    News & Views
  • Populations of river fish are threatened by pressures on land and water resources. Networks of reserves managed by Indigenous people at community level offer a way to conserve fish diversity and enhance yields of nearby fisheries.

    • Edward H. Allison
    • Violet Cho
    News & Views
  • Structural data revealing how an anti-tuberculosis drug works could aid efforts to improve therapeutic options for the disease. The findings also uncover aspects of how the drug’s target, the ATP synthase enzyme, operates.

    • Valerie Mizrahi
    • Clifton E. Barry III
    News & Views
  • Computational models show that regionally varied prices for carbon emissions can greatly reduce the need for poor countries to receive financial assistance to tackle climate change, while still stabilizing global warming.

    • Wei Peng
    News & Views
  • An analogue of the psychedelic drug ibogaine has been developed. The analogue mirrors ibogaine’s ability to treat addiction and depression in animal models, has fewer side effects and is much simpler to synthesize.

    • Gabriela Manzano-Nieves
    • Conor Liston
    News & Views
  • Neurons progressively deteriorate with age and lose resilience to injury. It emerges that treatment with three transcription factors can re-endow neurons in the mature eye with youthful characteristics and the capacity to regenerate.

    • Andrew D. Huberman
    News & Views
  • Microscopy methods that reveal the spatial patterns of individual types of microbe are limited by the number of different species that can be monitored together. A new technique now provides progress on this front.

    • Jen Nguyen
    • Carolina Tropini
    News & Views