Latest Research

  • Letter |

    In the ant genus Pheidole the growth of rudimentary wing discs—which influence developmental allometry to produce castes with distinct morphologies—is socially regulated to determine the worker-to-soldier ratio in Pheidole colonies.

    • Rajendhran Rajakumar
    • , Sophie Koch
    • , Mélanie Couture
    • , Marie-Julie Favé
    • , Angelica Lillico-Ouachour
    • , Travis Chen
    • , Giovanna De Blasis
    • , Arjuna Rajakumar
    • , Dominic Ouellette
    •  & Ehab Abouheif
  • Article | | open

    Deep phenotype and genome-wide genetic data from 500,000 individuals from the UK Biobank, describing population structure and relatedness in the cohort, and imputation to increase the number of testable variants to 96 million.

    • Clare Bycroft
    • , Colin Freeman
    • , Desislava Petkova
    • , Gavin Band
    • , Lloyd T. Elliott
    • , Kevin Sharp
    • , Allan Motyer
    • , Damjan Vukcevic
    • , Olivier Delaneau
    • , Jared O’Connell
    • , Adrian Cortes
    • , Samantha Welsh
    • , Alan Young
    • , Mark Effingham
    • , Gil McVean
    • , Stephen Leslie
    • , Naomi Allen
    • , Peter Donnelly
    •  & Jonathan Marchini
  • Letter |

    Simulations of commonly proposed forest-management portfolios for Europe show that no single portfolio would meet all the requirements of the Paris Agreement, and climate benefits from forest management would be modest and local.

    • Sebastiaan Luyssaert
    • , Guillaume Marie
    • , Aude Valade
    • , Yi-Ying Chen
    • , Sylvestre Njakou Djomo
    • , James Ryder
    • , Juliane Otto
    • , Kim Naudts
    • , Anne Sofie Lansø
    • , Josefine Ghattas
    •  & Matthew J. McGrath
  • Article |

    Lipopeptides secreted by Bacillus bacteria block quorum sensing by Staphylococcus aureus and thereby inhibit the growth of this opportunistic pathogen in the gut, suggesting why people in rural Thailand who are colonized by Bacillus are not also colonized by S. aureus.

    • Pipat Piewngam
    • , Yue Zheng
    • , Thuan H. Nguyen
    • , Seth W. Dickey
    • , Hwang-Soo Joo
    • , Amer E. Villaruz
    • , Kyle A. Glose
    • , Emilie L. Fisher
    • , Rachelle L. Hunt
    • , Barry Li
    • , Janice Chiou
    • , Sujiraphong Pharkjaksu
    • , Sunisa Khongthong
    • , Gordon Y. C. Cheung
    • , Pattarachai Kiratisin
    •  & Michael Otto
  • Letter |

    A strategy for managing the compositional distribution in metal halide perovskite light-emitting diodes enables them to surpass 20% external quantum efficiency—a step towards their practical application in lighting and displays.

    • Kebin Lin
    • , Jun Xing
    • , Li Na Quan
    • , F. Pelayo García de Arquer
    • , Xiwen Gong
    • , Jianxun Lu
    • , Liqiang Xie
    • , Weijie Zhao
    • , Di Zhang
    • , Chuanzhong Yan
    • , Wenqiang Li
    • , Xinyi Liu
    • , Yan Lu
    • , Jeffrey Kirman
    • , Edward H. Sargent
    • , Qihua Xiong
    •  & Zhanhua Wei
  • Article |

    A global model finds that the environmental impacts of the food system could increase by 60–90% by 2050, and that dietary changes, improvements in technologies and management, and reductions in food loss and waste will all be needed to mitigate these impacts.

    • Marco Springmann
    • , Michael Clark
    • , Daniel Mason-D’Croz
    • , Keith Wiebe
    • , Benjamin Leon Bodirsky
    • , Luis Lassaletta
    • , Wim de Vries
    • , Sonja J. Vermeulen
    • , Mario Herrero
    • , Kimberly M. Carlson
    • , Malin Jonell
    • , Max Troell
    • , Fabrice DeClerck
    • , Line J. Gordon
    • , Rami Zurayk
    • , Peter Scarborough
    • , Mike Rayner
    • , Brent Loken
    • , Jess Fanzo
    • , H. Charles J. Godfray
    • , David Tilman
    • , Johan Rockström
    •  & Walter Willett
  • Letter |

    Conditional deletion of Insm1 in mice demonstrates that INSM1 is the key switch that causes the maturation of outer hair cells in the cochlea, with its absence resulting in an increase in inner hair cells instead.

    • Teerawat Wiwatpanit
    • , Sarah M. Lorenzen
    • , Jorge A. Cantú
    • , Chuan Zhi Foo
    • , Ann K. Hogan
    • , Freddie Márquez
    • , John C. Clancy
    • , Matthew J. Schipma
    • , Mary Ann Cheatham
    • , Anne Duggan
    •  & Jaime García-Añoveros
  • Letter |

    A fundamental electronic noise—beyond electronic thermal noise and voltage-activated shot noise—that is generated by temperature differences across nanoscale conductors is demonstrated, with possible implications for thermometry and electronics.

    • Ofir Shein Lumbroso
    • , Lena Simine
    • , Abraham Nitzan
    • , Dvira Segal
    •  & Oren Tal
  • Letter |

    In human and mouse models of ovarian cancer, endoplasmic reticulum stress and the activation of the IRE1α–XBP1 pathway decreases the metabolic fitness of T cells and limits their anti-tumour functions.

    • Minkyung Song
    • , Tito A. Sandoval
    • , Chang-Suk Chae
    • , Sahil Chopra
    • , Chen Tan
    • , Melanie R. Rutkowski
    • , Mahesh Raundhal
    • , Ricardo A. Chaurio
    • , Kyle K. Payne
    • , Csaba Konrad
    • , Sarah E. Bettigole
    • , Hee Rae Shin
    • , Michael J. P. Crowley
    • , Juan P. Cerliani
    • , Andrew V. Kossenkov
    • , Ievgen Motorykin
    • , Sheng Zhang
    • , Giovanni Manfredi
    • , Dmitriy Zamarin
    • , Kevin Holcomb
    • , Paulo C. Rodriguez
    • , Gabriel A. Rabinovich
    • , Jose R. Conejo-Garcia
    • , Laurie H. Glimcher
    •  & Juan R. Cubillos-Ruiz
  • Letter |

    The formation of submicrometre-scale structure in perovskite light-emitting diodes can raise their external quantum efficiency beyond 20%, suggesting the possibility of both high efficiency and high brightness.

    • Yu Cao
    • , Nana Wang
    • , He Tian
    • , Jingshu Guo
    • , Yingqiang Wei
    • , Hong Chen
    • , Yanfeng Miao
    • , Wei Zou
    • , Kang Pan
    • , Yarong He
    • , Hui Cao
    • , You Ke
    • , Mengmeng Xu
    • , Ying Wang
    • , Ming Yang
    • , Kai Du
    • , Zewu Fu
    • , Decheng Kong
    • , Daoxin Dai
    • , Yizheng Jin
    • , Gongqiang Li
    • , Hai Li
    • , Qiming Peng
    • , Jianpu Wang
    •  & Wei Huang
  • Letter |

    A large-scale survey of fast radio bursts—short pulses of radio waves that seem to come from cosmological distances—finds 20 such events, including both the nearest and the most energetic bursts observed so far.

    • R. M. Shannon
    • , J.-P. Macquart
    • , K. W. Bannister
    • , R. D. Ekers
    • , C. W. James
    • , S. Osłowski
    • , H. Qiu
    • , M. Sammons
    • , A. W. Hotan
    • , M. A. Voronkov
    • , R. J. Beresford
    • , M. Brothers
    • , A. J. Brown
    • , J. D. Bunton
    • , A. P. Chippendale
    • , C. Haskins
    • , M. Leach
    • , M. Marquarding
    • , D. McConnell
    • , M. A. Pilawa
    • , E. M. Sadler
    • , E. R. Troup
    • , J. Tuthill
    • , M. T. Whiting
    • , J. R. Allison
    • , C. S. Anderson
    • , M. E. Bell
    • , J. D. Collier
    • , G. Gürkan
    • , G. Heald
    •  & C. J. Riseley
  • Article | | open

    Genome-wide association studies of brain imaging data from 8,428 individuals in UK Biobank show that many of the 3,144 traits studied are heritable, and genes associated with individual phenotypes are identified.

    • Lloyd T. Elliott
    • , Kevin Sharp
    • , Fidel Alfaro-Almagro
    • , Sinan Shi
    • , Karla L. Miller
    • , Gwenaëlle Douaud
    • , Jonathan Marchini
    •  & Stephen M. Smith
  • Letter |

    A population of cervical interneurons is identified that can regulate diaphragm function by modulating phrenic motor neurons; targeting this small population of neurons may be a functional strategy to restore breathing after traumatic spinal cord injury.

    • Kajana Satkunendrarajah
    • , Spyridon K. Karadimas
    • , Alex M. Laliberte
    • , Gaspard Montandon
    •  & Michael G. Fehlings
  • Letter |

    Neural blastocyst complementation creates a vacant forebrain niche in host embryos that can be populated by donor embryonic stem cell-derived dorsal telencephalic progenitors, resulting in a mouse brain organogenesis model.

    • Amelia N. Chang
    • , Zhuoyi Liang
    • , Hai-Qiang Dai
    • , Aimee M. Chapdelaine-Williams
    • , Nick Andrews
    • , Roderick T. Bronson
    • , Bjoern Schwer
    •  & Frederick W. Alt
  • Letter |

    A part-light, part-matter exciton-polariton topological insulator is created in an array of semiconductor microcavities.

    • S. Klembt
    • , T. H. Harder
    • , O. A. Egorov
    • , K. Winkler
    • , R. Ge
    • , M. A. Bandres
    • , M. Emmerling
    • , L. Worschech
    • , T. C. H. Liew
    • , M. Segev
    • , C. Schneider
    •  & S. Höfling
  • Letter |

    When basal cell carcinoma is treated with a Smoothened inhibitor, a subset of cancer cells evades treatment by switching identity, allowing residual tumours to regrow when treatment is discontinued.

    • Brian Biehs
    • , Gerrit J. P. Dijkgraaf
    • , Robert Piskol
    • , Bruno Alicke
    • , Soufiane Boumahdi
    • , Franklin Peale
    • , Stephen E. Gould
    •  & Frederic J. de Sauvage
  • Letter |

    Integrating an optical Kerr frequency comb source with an electronically excited laser pump produces a battery-powered comb generator that does not require external lasers, moveable optics or laboratory set-ups.

    • Brian Stern
    • , Xingchen Ji
    • , Yoshitomo Okawachi
    • , Alexander L. Gaeta
    •  & Michal Lipson
  • Letter |

    Treatment of basal cell carcinoma with Smoothened inhibitors leaves a small population of quiescent cells that can drive relapse but can be eliminated by additional treatment with a Wnt signalling inhibitor.

    • Adriana Sánchez-Danés
    • , Jean-Christophe Larsimont
    • , Mélanie Liagre
    • , Eva Muñoz-Couselo
    • , Gaëlle Lapouge
    • , Audrey Brisebarre
    • , Christine Dubois
    • , Mariano Suppa
    • , Vijayakumar Sukumaran
    • , Véronique del Marmol
    • , Josep Tabernero
    •  & Cédric Blanpain
  • Letter |

    By intercalating large ammonium molecules to exfoliate MoS2 with preservation of the 2H-phase, highly uniform solutionprocessable 2D semiconductor nanosheets are obtained for the scalable fabrication of large-area thin-film electronics.

    • Zhaoyang Lin
    • , Yuan Liu
    • , Udayabagya Halim
    • , Mengning Ding
    • , Yuanyue Liu
    • , Yiliu Wang
    • , Chuancheng Jia
    • , Peng Chen
    • , Xidong Duan
    • , Chen Wang
    • , Frank Song
    • , Mufan Li
    • , Chengzhang Wan
    • , Yu Huang
    •  & Xiangfeng Duan
  • Review Article |

    The current state of the search for dark-matter particles is reviewed, and a broader experimental and theoretical approach is proposed to solve the dark-matter problem.

    • Gianfranco Bertone
    •  & Tim M. P. Tait
  • Letter |

    The transcription factor OTX2 ensures that germline induction is initially kept in check and only proceeds after OTX2 downregulation.

    • Jingchao Zhang
    • , Man Zhang
    • , Dario Acampora
    • , Matúš Vojtek
    • , Detian Yuan
    • , Antonio Simeone
    •  & Ian Chambers
  • Letter |

    Observations of teraelectronvolt γ-rays accelerated by the jets of the miniature quasar SS 433 are reported.

    • A. U. Abeysekara
    • , A. Albert
    • , R. Alfaro
    • , C. Alvarez
    • , J. D. Álvarez
    • , R. Arceo
    • , J. C. Arteaga-Velázquez
    • , D. Avila Rojas
    • , H. A. Ayala Solares
    • , E. Belmont-Moreno
    • , S. Y. BenZvi
    • , C. Brisbois
    • , K. S. Caballero-Mora
    • , T. Capistrán
    • , A. Carramiñana
    • , S. Casanova
    • , M. Castillo
    • , U. Cotti
    • , J. Cotzomi
    • , S. Coutiño de León
    • , C. De León
    • , E. De la Fuente
    • , J. C. Díaz-Vélez
    • , S. Dichiara
    • , B. L. Dingus
    • , M. A. DuVernois
    • , R. W. Ellsworth
    • , K. Engel
    • , C. Espinoza
    • , K. Fang
    • , H. Fleischhack
    • , N. Fraija
    • , A. Galván-Gámez
    • , J. A. García-González
    • , F. Garfias
    • , A. González-Muñoz
    • , M. M. González
    • , J. A. Goodman
    • , Z. Hampel-Arias
    • , J. P. Harding
    • , S. Hernandez
    • , J. Hinton
    • , B. Hona
    • , F. Hueyotl-Zahuantitla
    • , C. M. Hui
    • , P. Hüntemeyer
    • , A. Iriarte
    • , A. Jardin-Blicq
    • , V. Joshi
    • , S. Kaufmann
    • , P. Kar
    • , G. J. Kunde
    • , R. J. Lauer
    • , W. H. Lee
    • , H. León Vargas
    • , H. Li
    • , J. T. Linnemann
    • , A. L. Longinotti
    • , G. Luis-Raya
    • , R. López-Coto
    • , K. Malone
    • , S. S. Marinelli
    • , O. Martinez
    • , I. Martinez-Castellanos
    • , J. Martínez-Castro
    • , J. A. Matthews
    • , P. Miranda-Romagnoli
    • , E. Moreno
    • , M. Mostafá
    • , A. Nayerhoda
    • , L. Nellen
    • , M. Newbold
    • , M. U. Nisa
    • , R. Noriega-Papaqui
    • , J. Pretz
    • , E. G. Pérez-Pérez
    • , Z. Ren
    • , C. D. Rho
    • , C. Rivière
    • , D. Rosa-González
    • , M. Rosenberg
    • , E. Ruiz-Velasco
    • , F. Salesa Greus
    • , A. Sandoval
    • , M. Schneider
    • , H. Schoorlemmer
    • , M. Seglar Arroyo
    • , G. Sinnis
    • , A. J. Smith
    • , R. W. Springer
    • , P. Surajbali
    • , I. Taboada
    • , O. Tibolla
    • , K. Tollefson
    • , I. Torres
    • , G. Vianello
    • , L. Villaseñor
    • , T. Weisgarber
    • , F. Werner
    • , S. Westerhoff
    • , J. Wood
    • , T. Yapici
    • , G. Yodh
    • , A. Zepeda
    • , H. Zhang
    •  & H. Zhou
  • Letter |

    This approach introduces an aryl substituent to the α-carbon of amino acids without a transition-metal catalyst, and uses the inherent chirality of the amino acid itself as the source of asymmetry.

    • Daniel J. Leonard
    • , John W. Ward
    •  & Jonathan Clayden
  • Letter |

    Crystal structures of DltB, a bacterial membrane-bound O-acyltransferase, are reported both alone and in complex with the d-alanyl donor protein DltC.

    • Dan Ma
    • , Zhizhi Wang
    • , Christopher N. Merrikh
    • , Kevin S. Lang
    • , Peilong Lu
    • , Xin Li
    • , Houra Merrikh
    • , Zihe Rao
    •  & Wenqing Xu
  • Letter |

    Low soil moisture may reduce, or even reverse, the potential benefits of climate warming on photosynthesis in mesic, seasonally cold environments, both during drought and in regularly occurring, modestly dry periods during the growing season.

    • Peter B. Reich
    • , Kerrie M. Sendall
    • , Artur Stefanski
    • , Roy L. Rich
    • , Sarah E. Hobbie
    •  & Rebecca A. Montgomery
  • Letter |

    An organic copolymer with compositionally tailored tacticity exhibits behaviour reminiscent of a morphotropic phase boundary, with an intramolecular order-to-disorder transition in the crystalline phase and a very large piezoelectric coefficient.

    • Yang Liu
    • , Haibibu Aziguli
    • , Bing Zhang
    • , Wenhan Xu
    • , Wenchang Lu
    • , J. Bernholc
    •  & Qing Wang
  • Letter |

    The structure of a pilus assembly intermediate reveals the timing of subunit polymerization and how chaperone–subunit complexes are transferred from N-terminal to C-terminal domains of the usher in the formation of bacterial pili.

    • Minge Du
    • , Zuanning Yuan
    • , Hongjun Yu
    • , Nadine Henderson
    • , Samema Sarowar
    • , Gongpu Zhao
    • , Glenn T. Werneburg
    • , David G. Thanassi
    •  & Huilin Li
  • Letter |

    Cultures grown from small aggregates of mouse embryonic stem cells can be induced to organize spatial and temporal patterns of gene expression that parallel those of the early embryo, offering a potentially useful system for studying early development.

    • Leonardo Beccari
    • , Naomi Moris
    • , Mehmet Girgin
    • , David A. Turner
    • , Peter Baillie-Johnson
    • , Anne-Catherine Cossy
    • , Matthias P. Lutolf
    • , Denis Duboule
    •  & Alfonso Martinez Arias
  • Article |

    An RNA-adapting CRISPR–Cas system is coupled with amplification and sequencing steps to record, retrieve and analyse changes in the transcriptome of a bacterial cell over time.

    • Florian Schmidt
    • , Mariia Y. Cherepkova
    •  & Randall J. Platt
  • Article |

    In monkeys infected with an AIDS-like virus, a combination of a broadly neutralizing antibody and an immune stimulator during antiretroviral therapy suppressed viral rebound after antiretroviral drug discontinuation.

    • Erica N. Borducchi
    • , Jinyan Liu
    • , Joseph P. Nkolola
    • , Anthony M. Cadena
    • , Wen-Han Yu
    • , Stephanie Fischinger
    • , Thomas Broge
    • , Peter Abbink
    • , Noe B. Mercado
    • , Abishek Chandrashekar
    • , David Jetton
    • , Lauren Peter
    • , Katherine McMahan
    • , Edward T. Moseley
    • , Elena Bekerman
    • , Joseph Hesselgesser
    • , Wenjun Li
    • , Mark G. Lewis
    • , Galit Alter
    • , Romas Geleziunas
    •  & Dan H. Barouch
  • Article |

    A ‘mouse atlas’, comprising single-cell transcriptomic data from more than 100,000 cells from 20 organs and tissues, has been created as a resource for cell biology.

    • Nicholas Schaum
    • , Jim Karkanias
    • , Norma F. Neff
    • , Andrew P. May
    • , Stephen R. Quake
    • , Tony Wyss-Coray
    • , Spyros Darmanis
    • , Joshua Batson
    • , Olga Botvinnik
    • , Michelle B. Chen
    • , Steven Chen
    • , Foad Green
    • , Robert C. Jones
    • , Ashley Maynard
    • , Lolita Penland
    • , Angela Oliveira Pisco
    • , Rene V. Sit
    • , Geoffrey M. Stanley
    • , James T. Webber
    • , Fabio Zanini
    • , Ankit S. Baghel
    • , Isaac Bakerman
    • , Ishita Bansal
    • , Daniela Berdnik
    • , Biter Bilen
    • , Douglas Brownfield
    • , Corey Cain
    • , Michelle B. Chen
    • , Steven Chen
    • , Min Cho
    • , Giana Cirolia
    • , Stephanie D. Conley
    • , Spyros Darmanis
    • , Aaron Demers
    • , Kubilay Demir
    • , Antoine de Morree
    • , Tessa Divita
    • , Haley du Bois
    • , Laughing Bear Torrez Dulgeroff
    • , Hamid Ebadi
    • , F. Hernán Espinoza
    • , Matt Fish
    • , Qiang Gan
    • , Benson M. George
    • , Astrid Gillich
    • , Foad Green
    • , Geraldine Genetiano
    • , Xueying Gu
    • , Gunsagar S. Gulati
    • , Yan Hang
    • , Shayan Hosseinzadeh
    • , Albin Huang
    • , Tal Iram
    • , Taichi Isobe
    • , Feather Ives
    • , Robert C. Jones
    • , Kevin S. Kao
    • , Guruswamy Karnam
    • , Aaron M. Kershner
    • , Bernhard M. Kiss
    • , William Kong
    • , Maya E. Kumar
    • , Jonathan Y. Lam
    • , Davis P. Lee
    • , Song E. Lee
    • , Guang Li
    • , Qingyun Li
    • , Ling Liu
    • , Annie Lo
    • , Wan-Jin Lu
    • , Anoop Manjunath
    • , Andrew P. May
    • , Kaia L. May
    • , Oliver L. May
    • , Ashley Maynard
    • , Marina McKay
    • , Ross J. Metzger
    • , Marco Mignardi
    • , Dullei Min
    • , Ahmad N. Nabhan
    • , Norma F. Neff
    • , Katharine M. Ng
    • , Joseph Noh
    • , Rasika Patkar
    • , Weng Chuan Peng
    • , Lolita Penland
    • , Robert Puccinelli
    • , Eric J. Rulifson
    • , Nicholas Schaum
    • , Shaheen S. Sikandar
    • , Rahul Sinha
    • , Rene V. Sit
    • , Krzysztof Szade
    • , Weilun Tan
    • , Cristina Tato
    • , Krissie Tellez
    • , Kyle J. Travaglini
    • , Carolina Tropini
    • , Lucas Waldburger
    • , Linda J. van Weele
    • , Michael N. Wosczyna
    • , Jinyi Xiang
    • , Soso Xue
    • , Justin Youngyunpipatkul
    • , Fabio Zanini
    • , Macy E. Zardeneta
    • , Fan Zhang
    • , Lu Zhou
    • , Ishita Bansal
    • , Steven Chen
    • , Min Cho
    • , Giana Cirolia
    • , Spyros Darmanis
    • , Aaron Demers
    • , Tessa Divita
    • , Hamid Ebadi
    • , Geraldine Genetiano
    • , Foad Green
    • , Shayan Hosseinzadeh
    • , Feather Ives
    • , Annie Lo
    • , Andrew P. May
    • , Ashley Maynard
    • , Marina McKay
    • , Norma F. Neff
    • , Lolita Penland
    • , Rene V. Sit
    • , Weilun Tan
    • , Lucas Waldburger
    • , Justin Youngyunpipatkul
    • , Joshua Batson
    • , Olga Botvinnik
    • , Paola Castro
    • , Derek Croote
    • , Spyros Darmanis
    • , Joseph L. DeRisi
    • , Jim Karkanias
    • , Angela Oliveira Pisco
    • , Geoffrey M. Stanley
    • , James T. Webber
    • , Fabio Zanini
    • , Ankit S. Baghel
    • , Isaac Bakerman
    • , Joshua Batson
    • , Biter Bilen
    • , Olga Botvinnik
    • , Douglas Brownfield
    • , Michelle B. Chen
    • , Spyros Darmanis
    • , Kubilay Demir
    • , Antoine de Morree
    • , Hamid Ebadi
    • , F. Hernán Espinoza
    • , Matt Fish
    • , Qiang Gan
    • , Benson M. George
    • , Astrid Gillich
    • , Xueying Gu
    • , Gunsagar S. Gulati
    • , Yan Hang
    • , Albin Huang
    • , Tal Iram
    • , Taichi Isobe
    • , Guruswamy Karnam
    • , Aaron M. Kershner
    • , Bernhard M. Kiss
    • , William Kong
    • , Christin S. Kuo
    • , Jonathan Y. Lam
    • , Benoit Lehallier
    • , Guang Li
    • , Qingyun Li
    • , Ling Liu
    • , Wan-Jin Lu
    • , Dullei Min
    • , Ahmad N. Nabhan
    • , Katharine M. Ng
    • , Patricia K. Nguyen
    • , Rasika Patkar
    • , Weng Chuan Peng
    • , Lolita Penland
    • , Eric J. Rulifson
    • , Nicholas Schaum
    • , Shaheen S. Sikandar
    • , Rahul Sinha
    • , Krzysztof Szade
    • , Serena Y. Tan
    • , Krissie Tellez
    • , Kyle J. Travaglini
    • , Carolina Tropini
    • , Linda J. van Weele
    • , Bruce M. Wang
    • , Michael N. Wosczyna
    • , Jinyi Xiang
    • , Hanadie Yousef
    • , Lu Zhou
    • , Joshua Batson
    • , Olga Botvinnik
    • , Steven Chen
    • , Spyros Darmanis
    • , Foad Green
    • , Andrew P. May
    • , Ashley Maynard
    • , Angela Oliveira Pisco
    • , Stephen R. Quake
    • , Nicholas Schaum
    • , Geoffrey M. Stanley
    • , James T. Webber
    • , Tony Wyss-Coray
    • , Fabio Zanini
    • , Philip A. Beachy
    • , Charles K. F. Chan
    • , Antoine de Morree
    • , Benson M. George
    • , Gunsagar S. Gulati
    • , Yan Hang
    • , Kerwyn Casey Huang
    • , Tal Iram
    • , Taichi Isobe
    • , Aaron M. Kershner
    • , Bernhard M. Kiss
    • , William Kong
    • , Guang Li
    • , Qingyun Li
    • , Ling Liu
    • , Wan-Jin Lu
    • , Ahmad N. Nabhan
    • , Katharine M. Ng
    • , Patricia K. Nguyen
    • , Weng Chuan Peng
    • , Eric J. Rulifson
    • , Nicholas Schaum
    • , Shaheen S. Sikandar
    • , Rahul Sinha
    • , Krzysztof Szade
    • , Kyle J. Travaglini
    • , Carolina Tropini
    • , Bruce M. Wang
    • , Kenneth Weinberg
    • , Michael N. Wosczyna
    • , Sean M. Wu
    • , Hanadie Yousef
    • , Ben A. Barres
    • , Philip A. Beachy
    • , Charles K. F. Chan
    • , Michael F. Clarke
    • , Spyros Darmanis
    • , Kerwyn Casey Huang
    • , Jim Karkanias
    • , Seung K. Kim
    • , Mark A. Krasnow
    • , Maya E. Kumar
    • , Christin S. Kuo
    • , Andrew P. May
    • , Ross J. Metzger
    • , Norma F. Neff
    • , Roel Nusse
    • , Patricia K. Nguyen
    • , Thomas A. Rando
    • , Justin Sonnenburg
    • , Bruce M. Wang
    • , Kenneth Weinberg
    • , Irving L. Weissman
    • , Sean M. Wu
    • , Stephen R. Quake
    •  & Tony Wyss-Coray
  • Letter |

    Widespread but contrasting delayed responses of ecosystem productivity to spring warmth across northern ecosystems is inferred from satellite data, with higher areal fractions of adverse effects than beneficial effects.

    • Wolfgang Buermann
    • , Matthias Forkel
    • , Michael O’Sullivan
    • , Stephen Sitch
    • , Pierre Friedlingstein
    • , Vanessa Haverd
    • , Atul K. Jain
    • , Etsushi Kato
    • , Markus Kautz
    • , Sebastian Lienert
    • , Danica Lombardozzi
    • , Julia E. M. S. Nabel
    • , Hanqin Tian
    • , Andrew J. Wiltshire
    • , Dan Zhu
    • , William K. Smith
    •  & Andrew D. Richardson
  • Letter |

    Lyman-α emission from atomic hydrogen shows the location of warm gas and is ubiquitous around galaxies between redshifts of 3 and 6, thereby covering nearly all the sky.

    • L. Wisotzki
    • , R. Bacon
    • , J. Brinchmann
    • , S. Cantalupo
    • , P. Richter
    • , J. Schaye
    • , K. B. Schmidt
    • , T. Urrutia
    • , P. M. Weilbacher
    • , M. Akhlaghi
    • , N. Bouché
    • , T. Contini
    • , B. Guiderdoni
    • , E. C. Herenz
    • , H. Inami
    • , J. Kerutt
    • , F. Leclercq
    • , R. A. Marino
    • , M. Maseda
    • , A. Monreal-Ibero
    • , T. Nanayakkara
    • , J. Richard
    • , R. Saust
    • , M. Steinmetz
    •  & M. Wendt
  • Letter |

    DEET interferes selectively with chemotaxis of Caenorhabditis elegans nematodes, and mutations in the str-217 gene or silencing of the pair of chemosensory neurons that express it makes worms DEET-resistant.

    • Emily J. Dennis
    • , May Dobosiewicz
    • , Xin Jin
    • , Laura B. Duvall
    • , Philip S. Hartman
    • , Cornelia I. Bargmann
    •  & Leslie B. Vosshall
  • Letter |

    Observations of a jet from a strongly magnetized neutron star reveal that strong magnetic fields do not prevent jet formation and suggest that stellar properties influence jet power.

    • J. van den Eijnden
    • , N. Degenaar
    • , T. D. Russell
    • , R. Wijnands
    • , J. C. A. Miller-Jones
    • , G. R. Sivakoff
    •  & J. V. Hernández Santisteban
  • Article |

    Combination therapy with the anti-HIV-1 monoclonal antibodies 3BNC117 and 10-1074 maintains long-term suppression in the absence of antiretroviral therapy in individuals with antibody-sensitive viral reservoirs.

    • Pilar Mendoza
    • , Henning Gruell
    • , Lilian Nogueira
    • , Joy A. Pai
    • , Allison L. Butler
    • , Katrina Millard
    • , Clara Lehmann
    • , Isabelle Suárez
    • , Thiago Y. Oliveira
    • , Julio C. C. Lorenzi
    • , Yehuda Z. Cohen
    • , Christoph Wyen
    • , Tim Kümmerle
    • , Theodora Karagounis
    • , Ching-Lan Lu
    • , Lisa Handl
    • , Cecilia Unson-O’Brien
    • , Roshni Patel
    • , Carola Ruping
    • , Maike Schlotz
    • , Maggi Witmer-Pack
    • , Irina Shimeliovich
    • , Gisela Kremer
    • , Eleonore Thomas
    • , Kelly E. Seaton
    • , Jill Horowitz
    • , Anthony P. West Jr
    • , Pamela J. Bjorkman
    • , Georgia D. Tomaras
    • , Roy M. Gulick
    • , Nico Pfeifer
    • , Gerd Fätkenheuer
    • , Michael S. Seaman
    • , Florian Klein
    • , Marina Caskey
    •  & Michel C. Nussenzweig
  • Article |

    Analyses of the relationships between temperature, moisture and seven key plant functional traits across the tundra and over time show that community height increased with warming across all sites, whereas other traits lagged behind predicted rates of change.

    • Anne D. Bjorkman
    • , Isla H. Myers-Smith
    • , Sarah C. Elmendorf
    • , Signe Normand
    • , Nadja Rüger
    • , Pieter S. A. Beck
    • , Anne Blach-Overgaard
    • , Daan Blok
    • , J. Hans C. Cornelissen
    • , Bruce C. Forbes
    • , Damien Georges
    • , Scott J. Goetz
    • , Kevin C. Guay
    • , Gregory H. R. Henry
    • , Janneke HilleRisLambers
    • , Robert D. Hollister
    • , Dirk N. Karger
    • , Jens Kattge
    • , Peter Manning
    • , Janet S. Prevéy
    • , Christian Rixen
    • , Gabriela Schaepman-Strub
    • , Haydn J. D. Thomas
    • , Mark Vellend
    • , Martin Wilmking
    • , Sonja Wipf
    • , Michele Carbognani
    • , Luise Hermanutz
    • , Esther Lévesque
    • , Ulf Molau
    • , Alessandro Petraglia
    • , Nadejda A. Soudzilovskaia
    • , Marko J. Spasojevic
    • , Marcello Tomaselli
    • , Tage Vowles
    • , Juha M. Alatalo
    • , Heather D. Alexander
    • , Alba Anadon-Rosell
    • , Sandra Angers-Blondin
    • , Mariska te Beest
    • , Logan Berner
    • , Robert G. Björk
    • , Agata Buchwal
    • , Allan Buras
    • , Katherine Christie
    • , Elisabeth J. Cooper
    • , Stefan Dullinger
    • , Bo Elberling
    • , Anu Eskelinen
    • , Esther R. Frei
    • , Oriol Grau
    • , Paul Grogan
    • , Martin Hallinger
    • , Karen A. Harper
    • , Monique M. P. D. Heijmans
    • , James Hudson
    • , Karl Hülber
    • , Maitane Iturrate-Garcia
    • , Colleen M. Iversen
    • , Francesca Jaroszynska
    • , Jill F. Johnstone
    • , Rasmus Halfdan Jørgensen
    • , Elina Kaarlejärvi
    • , Rebecca Klady
    • , Sara Kuleza
    • , Aino Kulonen
    • , Laurent J. Lamarque
    • , Trevor Lantz
    • , Chelsea J. Little
    • , James D. M. Speed
    • , Anders Michelsen
    • , Ann Milbau
    • , Jacob Nabe-Nielsen
    • , Sigrid Schøler Nielsen
    • , Josep M. Ninot
    • , Steven F. Oberbauer
    • , Johan Olofsson
    • , Vladimir G. Onipchenko
    • , Sabine B. Rumpf
    • , Philipp Semenchuk
    • , Rohan Shetti
    • , Laura Siegwart Collier
    • , Lorna E. Street
    • , Katharine N. Suding
    • , Ken D. Tape
    • , Andrew Trant
    • , Urs A. Treier
    • , Jean-Pierre Tremblay
    • , Maxime Tremblay
    • , Susanna Venn
    • , Stef Weijers
    • , Tara Zamin
    • , Noémie Boulanger-Lapointe
    • , William A. Gould
    • , David S. Hik
    • , Annika Hofgaard
    • , Ingibjörg S. Jónsdóttir
    • , Janet Jorgenson
    • , Julia Klein
    • , Borgthor Magnusson
    • , Craig Tweedie
    • , Philip A. Wookey
    • , Michael Bahn
    • , Benjamin Blonder
    • , Peter M. van Bodegom
    • , Benjamin Bond-Lamberty
    • , Giandiego Campetella
    • , Bruno E. L. Cerabolini
    • , F. Stuart Chapin III
    • , William K. Cornwell
    • , Joseph Craine
    • , Matteo Dainese
    • , Franciska T. de Vries
    • , Sandra Díaz
    • , Brian J. Enquist
    • , Walton Green
    • , Ruben Milla
    • , Ülo Niinemets
    • , Yusuke Onoda
    • , Jenny C. Ordoñez
    • , Wim A. Ozinga
    • , Josep Penuelas
    • , Hendrik Poorter
    • , Peter Poschlod
    • , Peter B. Reich
    • , Brody Sandel
    • , Brandon Schamp
    • , Serge Sheremetev
    •  & Evan Weiher
  • Letter |

    In mouse and human liver models, blood vessel perfusion and mechanical stretching release angiocrine signals from endothelial cells that lead to hepatocyte survival and liver growth.

    • Linda Lorenz
    • , Jennifer Axnick
    • , Tobias Buschmann
    • , Carina Henning
    • , Sofia Urner
    • , Shentong Fang
    • , Harri Nurmi
    • , Nicole Eichhorst
    • , Richard Holtmeier
    • , Kálmán Bódis
    • , Jong-Hee Hwang
    • , Karsten Müssig
    • , Daniel Eberhard
    • , Jörg Stypmann
    • , Oliver Kuss
    • , Michael Roden
    • , Kari Alitalo
    • , Dieter Häussinger
    •  & Eckhard Lammert
  • Letter |

    A scheme for implementing multi-step topological reorganization of a mechanical metamaterial is demonstrated, which proceeds autonomously, without the need for external control.

    • Corentin Coulais
    • , Alberico Sabbadini
    • , Fré Vink
    •  & Martin van Hecke
  • Brief Communications Arising |

    • Andy J. Chang
    • , Noah S. Kim
    • , Homza Hireed
    • , Alex Diaz de Arce
    • , Fabian E. Ortega
    • , Johannes Riegler
    • , Daniel V. Madison
    •  & Mark A. Krasnow