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hotoexcitation of a catalytic enzyme enzyme’s co-factor is shown to change the reactivity of the enzyme, enabling it to carry out a non-natural enantioselective dehalogenation of lactone molecules.
Here, the genome sequence of the tiger tail seahorse is reported and comparative genomic analyses with other ray-finned fishes are used to explore the genetic basis of the unique morphology and reproductive system of the seahorse.
Observations of the outflow associated with the TMC1A protostellar system reveal that the ‘disk wind’ model correctly explains how material is ejected from protostars.
Two complementary studies present the full-length high-resolution structure of a Slo1 channel in the presence or absence of Ca2+ ions, in which an unconventional allosteric voltage-sensing mechanism regulates the Ca2+ sensor in addition to the voltage sensor’s direct action on the pore.
The authors report the structure of the assembled membrane spanning ring forming proteins of the Salmonella Typhimurium injectisome basal body, including the first atomic structure of a member of the secretin family of outer-membrane pores.
Two complementary studies present the full-length high-resolution structure of a Slo1 channel in the presence or absence of Ca2+ ions, in which an unconventional allosteric voltage-sensing mechanism regulates the Ca2+ sensor in addition to the voltage sensor’s direct action on the pore.
A correlated blinking phenomenon is discovered in two-dimensional bilayer semiconductor heterostructures, whereby a bright emission state occurs in one monolayer while a dark state occurs in the other, and vice versa.
Two related papers show that cells disseminated from malignant lesions at early time points during tumorigenesis can contribute to metastases at distant organs and provide insights into the molecular basis of dissemination.
Two related papers show that cells disseminated from malignant lesions at early time points during tumorigenesis can contribute to metastases at distant organs and provide insights into the molecular basis of dissemination.
Treatment with signalling precursors of trehalose-6-phosphate allows light-triggered release of trehalose-6-phosphate in Arabidopsis thaliana and increases the yield and drought resistance of spring wheat (Triticum aestivum).
Mice deficient in the protein NLRC3 are highly prone to colitis and tumour development in the colon as NLRC3 suppresses the activation of mTOR signalling pathways that help drive tumorigenesis.
Heat shock drives the expression of transcripts that bypass mRNA quality control for direct export and translation, allowing cells to survive extreme situations at the cost of accuracy.
Records of iceberg-rafted debris and climate model simulations reveal that fluctuations in Antarctic Ice Sheet discharge may have amplified climate fluctuations during the Holocene.
The ratio of magnesium to iron abundance is measured for a massive quiescent galaxy at a redshift of 2.1, corresponding to when the Universe was three billion years old.
Measurements of cosmic-ray-produced 10Be and 26Al in a bedrock core from beneath the summit of the Greenland Ice Sheet show that Greenland was nearly ice-free for extended periods under Pleistocene climate forcing.
A freely available dataset produced from three million Landsat satellite images reveals substantial changes in the distribution of global surface water over the past 32 years and their causes, from climate change to human actions.