Table of Contents

Volume 544 Number 7651 pp393-514

27 April 2017

About the cover

Domesticated some 10,000 years ago, barley has been a key crop since the dawn of agriculture. In this week’s issue, Nils Stein and colleagues in the International Barley Sequencing Consortium report the sequencing and assembly of a reference genome for this important grain. They produced the genome for Hordeum vulgare L. by combining hierarchical shotgun sequencing of bacterial artificial chromosomes, genome mapping on nanochannel arrays and chromosome-scale scaffolding with conformation capture sequencing. The result is the first comprehensive, completely ordered assembly of the pericentromeric regions of a Triticeae genome — and it reveals that each of barley’s seven chromosomes is divided into three compartments. The authors also sequenced and examined genetic diversity in the exomes of 96 European elite barley lines with a spring or winter growth habit, highlighting the potential utility of the sequence for cereal genomics and breeding programmes. Cover image: Gerd Ludwig/NGC

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    • Martin Mascher
    • Heidrun Gundlach
    • Axel Himmelbach
    • Sebastian Beier
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    The International Barley Genome Sequencing Consortium reports sequencing and assembly of a reference genome for barley, Hordeum vulgare.

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