Nature 465, 492–496 (2010)

In this Letter, an experimental error affected the western blot analyses of mouse liver extracts shown in Fig. 4f and g. The secondary antibody cross-reacted with endogenous mouse IgG in the tissue lysates, resulting in incorrect bands. The experiments were repeated using different primary antibodies and a secondary antibody that showed no such cross-reactivity. Although there was a trend, the reduction of p-JNK and p-Jun in the livers of CD95-deficient mice in Fig. 4f was not statistically significant. In addition, although the increase in phosphorylated JNK and Jun in Jo2-injected mice was reproducible in Fig. 4g, Jun protein was also increased. Corrected versions of Fig. 4f and g are shown below. The Supplementary Methods have been updated to reflect the change in the use of antibodies, and Supplementary Fig. 8b has also been corrected. The corrected figures do not alter the overall conclusions of this Letter, and all other data still stand.

Figure 1
figure 1

Corrected Fig. 4f and g shown below