Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News and Views Q&A
  • Published:

Q&A: Cancer

Clues from cell metabolism

Nature volume 465, pages 562–564 (2010)Cite this article

Subjects

Interest in the abnormal metabolism exhibited by cancer cells has been reawakened by the discovery of oncogenic mutations in metabolic enzymes, and by tools that monitor metabolism in living cells. Existing and emerging therapies aim to target this abnormal metabolism in various ways.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Biochemistry of cancer-cell metabolism.
Figure 2: Regulation of HIF function.

Author information

Authors and Affiliations

  1. William G. Kaelin Jr is at the Howard Hughes Medical Institute, and at the Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. william_kaelin@dfci.harvard.edu; ,

    William G. Kaelin Jr

  2. Craig B. Thompson is at the Abramson Cancer Center and Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. craig@exchange.upenn.edu ,

    Craig B. Thompson

Authors
  1. William G. Kaelin Jr
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Craig B. Thompson
    View author publications

    You can also search for this author in PubMed Google Scholar

Ethics declarations

Competing interests

W.G.K. is a consultant to FibroGen Pharmaceuticals and to Agios Pharmaceuticals. C.B.T. is a founder and chair of the advisory board of Agios Pharmaceuticals.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kaelin, W., Thompson, C. Clues from cell metabolism. Nature 465, 562–564 (2010). https://doi.org/10.1038/465562a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/465562a

This article is cited by

Search

Advanced search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer