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Cell biology

Pore puzzle

Nature volume 450, pages 621–622 (2007)Cite this article

Where would you start in trying to work out the structure of a macromolecular machine consisting of 456 proteins? Taking a combined experimental and computational approach is one answer.

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Figure 1: Determining the structure of the nuclear pore complex.

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Authors and Affiliations

  1. John D. Aitchison is at the Institute for Systems Biology, 1441 North 34th Street, Seattle, Washington 98103, USA. jaitchison@systemsbiology.org ,

    John D. Aitchison

  2. Richard W. Wozniak is in the Department of Cell Biology, University of Alberta, Edmonton, Alberta T6G 2H7, Canada. rick.wozniak@ualberta.ca,

    Richard W. Wozniak

Authors
  1. John D. Aitchison
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  2. Richard W. Wozniak
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Aitchison, J., Wozniak, R. Pore puzzle. Nature 450, 621–622 (2007). https://doi.org/10.1038/450621a

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