Although they were discovered only in the early 1990s, many regulatory functions of microRNAs — naturally occurring short RNA sequences — have already been reported. The latest news is that they mediate cancer spread.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
DJ-1 upregulates breast cancer cell invasion by repressing KLF17 expression
British Journal of Cancer Open Access 06 February 2014
-
Co-expression module analysis reveals biological processes, genomic gain, and regulatory mechanisms associated with breast cancer progression
BMC Systems Biology Open Access 27 May 2010
-
The tumor microenvironment and its contribution to tumor evolution toward metastasis
Histochemistry and Cell Biology Open Access 06 November 2008
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
References
Steeg, P. S. Nature Med. 12, 895–904 (2006).
Ma, L., Teruya-Feldstein, J. & Weinberg, R. A. Nature 449, 682–688 (2007).
Kent, O. A. & Mendell, J. T. Oncogene 25, 6188–6196 (2006).
Iorio, M. V. et al. Cancer Res. 65, 7065–7070 (2005).
Yang, J. et al. Cell 117, 927–939 (2004).
Clark, E. A., Golub, T. R., Lander, E. S. & Hynes, R. O. Nature 406, 532–535 (2000).
Hakem, A. et al. Genes Dev. 19, 1974–1979 (2005).
Dews, M. et al. Nature Genet. 38, 1060–1065 (2006).
Dalmay, T. & Edwards, D. R. Oncogene 25, 6170–6175 (2006).
Hammond, S. M. Trends Mol. Med. 12, 99–101 (2006).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Steeg, P. Micromanagement of metastasis. Nature 449, 671–673 (2007). https://doi.org/10.1038/449671a
Published:
Issue Date:
DOI: https://doi.org/10.1038/449671a
This article is cited by
-
DJ-1 upregulates breast cancer cell invasion by repressing KLF17 expression
British Journal of Cancer (2014)
-
2-Hydroxycinnamaldehyde inhibits the epithelial-mesenchymal transition in breast cancer cells
Breast Cancer Research and Treatment (2013)
-
CCN5/WISP-2: A micromanager of breast cancer progression
Journal of Cell Communication and Signaling (2012)
-
Co-expression module analysis reveals biological processes, genomic gain, and regulatory mechanisms associated with breast cancer progression
BMC Systems Biology (2010)
-
MicroRNA-9 reduces cell invasion and E-cadherin secretion in SK-Hep-1 cell
Medical Oncology (2010)