Evolution has crafted thousands of enzymes that are efficient catalysts for a plethora of reactions. Human attempts at enzyme design trail far behind, but may benefit from exploiting evolutionary tactics.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Seelig, B. & Szostak, J. W. Nature 448, 828–831 (2007).
Jencks, W. P. Catalysis in Chemistry and Enzymology (Dover, Mineola, NY, 1987).
Schultz, P. G. & Lerner, R. A. Science 269, 1835–1842 (1995).
Keefe, A. D. & Szostak, J. W. Nature 410, 715–718 (2001).
Joyce, G. F. Science 315, 1507–1508 (2007).
Bartel, D. P. & Szostak, J. W. Science 261, 1411–1418 (1993).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Robertson, M., Scott, W. Designer enzymes. Nature 448, 757–758 (2007). https://doi.org/10.1038/448757a
Published:
Issue Date:
DOI: https://doi.org/10.1038/448757a