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Protein science

Discriminating taste of prions

Prions are infectious proteins that are involved in brain-wasting disorders such as mad cow disease. In yeast, specific sequences of amino acids in prions seem to mediate prion propagation and cross-species transmissibility.

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Figure 1: Principles of the immobilized-peptide array assay.

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Surewicz, W. Discriminating taste of prions. Nature 447, 541–542 (2007). https://doi.org/10.1038/447541b

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