Table of contents


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Editorials

Lunar dreams, again p589

There are rumblings from the White House about a grandiose vision for human space flight, ahead of President Bush's re-election campaign. If precedent is anything to go by, the results will be discomforting for NASA and for science.

doi:10.1038/426589a


A new home for molecular biologists p589

Celebrating a major relaunch of a Nature journal.

doi:10.1038/426589b


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News

Berkeley accused of biotech bias as ecologist is denied tenure p591

Rex Dalton

doi:10.1038/426591a


Ecologists attack endangered-species logjam p592

Betsy Mason

doi:10.1038/426592a


Swamp row bogs down Singapore's bid to reclaim land p592

David Cyranoski

doi:10.1038/426592b


Plague trial verdict leaves biologists split on biodefence p593

Erika Check

doi:10.1038/426593a


National Science Foundation facing budget let-down p593

Geoff Brumfiel

doi:10.1038/426593b


Mystery remains as journal withdraws paper p594

John Whitfield

doi:10.1038/426594a


Maths institute planned to meet multiplying demand p594

Jim Giles

doi:10.1038/426594b


Sheep horns downsized by hunters' taste for trophies p595

John Whitfield

doi:10.1038/426595a


Europe dithers over regulations for stem-cell research p595

Alison Abbott

doi:10.1038/426595b


News in brief p596

doi:10.1038/426596a


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News Feature

Boom, or bust? p598

Hundreds of millions of dollars are pouring into US biodefence research. You might expect scientists working on infectious diseases to be unequivocally delighted. But things aren't that simple, says Erika Check.

Erika Check

doi:10.1038/426598a


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Correspondence

QUAD system offers fair shares to all authors p602

Showing who did what could solve the problem of authorship abuse and disputes.

Justus V. Verhagen, Karin J. Wallace, Stephan C. Collins and Thomas R. Scott

doi:10.1038/426602a


Tidewater glaciers move at their own pace p602

W. T. Pfeffer

doi:10.1038/426602b


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Books and Arts

Playing God? p603

Scientists must let society decide on the ethics of reproductive technologies.

doi:10.1038/426603a


The two faces of consciousness p604

doi:10.1038/426604a


Rich rewards p604

doi:10.1038/426604b


Winging it p605

Mary Purton

doi:10.1038/426605a


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Concepts

Basic concepts: To put it simply... p607

Massimo Piattelli-Palmarini

doi:10.1038/426607a


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News and Views

ウイルスの進化:出番をうかがう流行病予備軍

Virus evolution: Epidemics-in-waiting p609

Could the next SARS-like virus reach epidemic proportions? Quantifying the likely threat of emerging diseases isn't easy, but evolution is a crucial factor that may tip the balance in favour of such human parasites.

Jim Bull and Dan Dykhuizen

doi:10.1038/426609a


量子光学:静止する光

Quantum optics: Light at a standstill p610

Nothing travels faster than light, but how slow can light go? Pulses of light have already been slowed to speeds of just a few metres per second, but now they have been brought to a complete halt.

Marlan O. Scully

doi:10.1038/426610a


化学:セルロースを積み上げる

Chemistry: Cellulose stacks up p611

The long chains of cellulose pack laterally into microfibrils of two crystalline forms. Comparison of the structures of these two forms reveals unexpected patterns of bonding that tie the chains together.

Mike Jarvis

doi:10.1038/426611a


地形学:自然と環境因子と地形

Geomorphology: Nature, nurture and landscape p612

Those studying erosion in mountain regions wrestle with factors such as what builds mountains, and how climate affects erosive forces. Yet perhaps a physically based theory is what is most needed.

Peter Molnar

doi:10.1038/426612a


100 and 50 years ago p613

doi:10.1038/426613a


シグナル伝達:一夫一婦制を守る分子

Signal transduction: Molecular monogamy p614

The interactions between cellular proteins must be highly specific, or cells will stop functioning. Some clever protein-manipulation experiments have revealed how this specificity has evolved in yeast.

Drew Endy and Michael B. Yaffe

doi:10.1038/426614a


キラリティー:一ひねりした有機フィルム

Chirality: Organic films with a twist p615

Left- and right-handed helical molecules form mirror-image chiral crystals on a copper substrate. It seems that the substrate and the molecules work in concert to determine the handedness of the crystal domains.

Michael D. Ward

doi:10.1038/426615a


Obituary: Bertram N. Brockhouse (1918–2003) p617

Tom Timusk

doi:10.1038/426617a


News and views in brief p618

doi:10.1038/426618a


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Brief Communications

Geomorphology: Solitary wave behaviour of sand dunes p619

Colliding dunes appear to traverse through one another and emerge unscathed.

Veit Schwämmle and Hans J. Herrmann

doi:10.1038/426619a


Genetics: Influence of TOR kinase on lifespan in C. elegans p620

Tibor Vellai, Krisztina Takacs-Vellai, Yue Zhang, Attila L. Kovacs, László Orosz and Fritz Müller

doi:10.1038/426620a


Metabolism: Ecology shapes bird bioenergetics p620

Brian K. McNab

doi:10.1038/426620b


Geochronology (communication arising): Dating of the Herto hominin fossils p621

Peter Faupl, Wolfram Richter and Christoph Urbanek

doi:10.1038/426621a


Geochronology (communication arising): Dating of the Herto hominin fossils p622

William K. Hart, Giday WoldeGabriel, Shigehiro Katoh, Paul R. Renne, Gen Suwa, Berhane Asfaw and Tim D. White

doi:10.1038/426622a


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Articles

感覚:嗅糸球間における中心-周辺抑制

Centre–surround inhibition among olfactory bulb glomeruli p623

J. L. Aungst, P. M. Heyward, A. C. Puche, S. V. Karnup, A. Hayar, G. Szabo and M. T. Shipley

doi:10.1038/nature02187


生化学:植物の光化学系Iの結晶構造

Crystal structure of plant photosystem I p630

Adam Ben-Shem, Felix Frolow and Nathan Nelson

doi:10.1038/nature02200


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Letters to Nature

宇宙:遠方にあるクェーサーにおける大質量星の爆発的形成の本質的な特徴

The essential signature of a massive starburst in a distant quasar p636

P. Solomon, P. Vanden Bout, C. Carilli and M. Guelin

doi:10.1038/nature02149


物理:原子媒質中の静止した光パルス

Stationary pulses of light in an atomic medium p638

M. Bajcsy, A. S. Zibrov and M. D. Lukin

doi:10.1038/nature02176


材料:単結晶基板上の薄膜におけるオフノーマル・ファイバー状テクスチャー

An off-normal fibre-like texture in thin films on single-crystal substrates p641

C. Detavernier, A. S. Özcan, J. Jordan-Sweet, E. A. Stach, J. Tersoff, F. M. Ross and C. Lavoie

doi:10.1038/nature02198


地球:ワシントン州カスケード山脈における降水量と長期浸食速度の空間変動相関

Coupled spatial variations in precipitation and long-term erosion rates across the Washington Cascades p645

Peter W. Reiners, Todd A. Ehlers, Sara G. Mitchell and David R. Montgomery

doi:10.1038/nature02111


地球:台湾造山帯における浸食、流出変動および地震活動の関係

Links between erosion, runoff variability and seismicity in the Taiwan orogen p648

Simon J. Dadson, Niels Hovius, Hongey Chen, W. Brian Dade, Meng-Long Hsieh, Sean D. Willett, Jyr-Ching Hu, Ming-Jame Horng, Meng-Chiang Chen, Colin P. Stark, Dimitri Lague and Jiun-Chuan Lin

doi:10.1038/nature02150


地球:ヒマラヤ山脈における浸食と降水量の分離

Decoupling of erosion and precipitation in the Himalayas p652

D. W. Burbank, A. E. Blythe, J. Putkonen, B. Pratt-Sitaula, E. Gabet, M. Oskin, A. Barros and T. P. Ojha

doi:10.1038/nature02187


生物保全:トロフィー狩猟がもたらす進化上好ましくない結果

Undesirable evolutionary consequences of trophy hunting p655

David W. Coltman, Paul O'Donoghue, Jon T. Jorgenson, John T. Hogg, Curtis Strobeck and Marco Festa-Bianchet

doi:10.1038/nature02177


進化:感染症の出現における進化の役割

The role of evolution in the emergence of infectious diseases p658

Rustom Antia, Roland R. Regoes, Jacob C. Koella and Carl T. Bergstrom

doi:10.1038/nature02104


生態:北海でマダラの加入にプランクトンが及ぼす影響

Plankton effect on cod recruitment in the North Sea p661

Grégory Beaugrand, Keith M. Brander, J. Alistair Lindley, Sami Souissi and Philip C. Reid

doi:10.1038/nature02164


視覚:物体形状の分解的処理は行動の視覚制御には必要だが視覚認知には不必要である

Visual control of action but not perception requires analytical processing of object shape p664

Tzvi Ganel and Melvyn A. Goodale

doi:10.1038/nature02156


視覚:一次視覚皮質に平行に入力する補色経路

Parallel colour-opponent pathways to primary visual cortex p668

Soumya Chatterjee and Edward M. Callaway

doi:10.1038/nature02167


免疫:BおよびTリンパ球の発生と維持には抗アポトーシス性MCL-1が必要である

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1 p671

Joseph T. Opferman, Anthony Letai, Caroline Beard, Mia D. Sorcinelli, Christy C. Ong and Stanley J. Korsmeyer

doi:10.1038/nature02067


細胞:負の選択による細胞タンパク質相互作用ネットワークにおける特異性の最適化

Optimization of specificity in a cellular protein interaction network by negative selection p676

Ali Zarrinpar, Sang-Hyun Park and Wendell A. Lim

doi:10.1038/nature02178


生理:植物で急速に起こる避陰反応の概日時計によるゲート開閉

Gating of the rapid shade-avoidance response by the circadian clock in plants p680

Michael G. Salter, Keara A. Franklin and Garry C. Whitelam

doi:10.1038/nature02174


生化学:塩基対レベルに近い分解能で観察した1個のRNAポリメラーゼ分子の後進

Backtracking by single RNA polymerase molecules observed at near-base-pair resolution p684

Joshua W. Shaevitz, Elio A. Abbondanzieri, Robert Landick and Steven M. Block

doi:10.1038/nature02191


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New on the Market

Spectroscopy and fluorescence p688

Flames, formats and photometry.

doi:10.1038/426688a


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Outlook

San Diego

San Diego p689

Ken Howard


Good neighbours p690

A tight-knit community and a cooperative spirit has helped San Diego to succeed. Eric Niiler checks out California's rising star.

Eric Niiler

doi:10.1038/426690


The view from the top p696

San Diego is facing significant challenges to its future development. How do the some of the region's leading lights think it will cope? Ken Howard finds out.

Ken Howard

doi:10.1038/426696


Genesis of a high-tech hub p700

A century of philanthropy alongside military research has laid solid foundations for today's diverse sci-tech sector, says Chloe Veltman.

Chloe Veltman

doi:10.1038/426700


Best of both worlds p706

What makes the Mesa so attractive to pharmaceutical companies? Paul Smaglik investigates.

Paul Smaglik

doi:10.1038/426706


Turning technology into gold p708

Scientists need help to make their entrepreneurial dreams come true. Jonathan Knight talks to the experts.

Jonathan Knight

doi:10.1038/426708


Tomorrow's world p709

Jonathan Knight takes a look at what the future may hold for innovation in San Diego.

Jonathan Knight

doi:10.1038/426709


Different directions? p712

How independent are the boards of San Diego's high-tech companies? Lisa Bowman investigates the multiple directors.

Lisa Bowman

doi:10.1038/426712


In search of the élite p713

A huge number of people have contributed to the success of San Diego. Virginia Gewin catches up with a selection of the region's prime movers.

Virginia Gewin

doi:10.1038/426713


High-tech, high society p720

Kendall Powell finds out how to make those key business connections.

Kendall Powell

doi:10.1038/426720


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Technology Features

To affinity and beyond p725

Antibodies are the researcher's Swiss army knife: there's a tool for every purpose, and they're made in more shapes and sizes than ever. Pete Moore and Julie Clayton report.

Pete Moore and Julie Clayton

doi:10.1038/426725a


Playing with the pieces p725

Pete Moore

doi:10.1038/426725b


Going into production p727

Julie Clayton

doi:10.1038/426727a


Antibodies where you want them p729

Pete Moore

doi:10.1038/426729a


Table of suppliers p732

doi:10.1038/426732a


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Naturejobs

Prospects

Forcing the market p735

Paul Smaglik

doi:10.1038/nj6967-736a


CAREERS AND RECRUITMENT

A developing theme for AIDS p736

Job growth in HIV research is shifting from laboratories in the developed world to the regions most affected by AIDS. Myrna Watanabe reports

Myrna Watanabe

doi:10.1038/nj6967-736a