Abstract
SINCE lymphocytes appear to play a crucial part in the homograft reaction it seemed of interest to examine the behaviour of homografts in recipients subjected to chronic lymphocyte depletion by: (a) drainage of lymph through a thoracic duct fistula; (b) repeated administration of a hetero-specific antilymphocytic serum; (c) a combination of these procedures.
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Gowans, J. L.,, McGregor, D. D., Cowen, D. M., and Ford, C. E., Nature, 196, 651 (1962).
Woodruff, M. F. A., The Transplantation of Tissues and Organs (C. C. Thomas, Springfield, Ill., 1960).
Woodruff, M. F. A., and Simpson, L. O., Plast. Reconstr. Surg., 15, 451 (1955).
Bollman, J. L., Cain, J. C., and Grindlay, J. H., J. Lab. Clin. Med., 33, 1349 (1948).
Gowans, J. L., Brit. J. Exp. Path., 38, 67 (1957).
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WOODRUFF, M., ANDERSON, N. Effect of Lymphocyte Depletion by Thoracic Duct Fistula and Administration of Antilymphocytic Serum on the Survival of Skin Homografts in Rats. Nature 200, 702 (1963). https://doi.org/10.1038/200702a0
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DOI: https://doi.org/10.1038/200702a0
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