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  • Special |

    Complete genome sequences have provided a plethora of potential drug targets. But the hard task of finding their weak spots is just beginning, as Caitlin Smith finds out.

  • Special |

    After NASA's lander Opportunity touched down safely over the weekend, we give the lowdown on this and other famous missions to the red planet.

  • Special |

    A one-stop shop for a selection of excellent articles and features on stem cells handpicked from the pages of Nature, including the specially commissioned Stem cell Insight.

  • Special |

    At between 6 and 7 million years old, Toumaï is the earliest known record of the human family. To celebrate the discovery of this skull, we are proud to offer a selection of ten of the very best from Nature's archives.

  • Insight |

    At school it all sounded so simple - transcription turns DNA into RNA, and translation of RNA gives you protein. But the often forgotten third step in this process, the folding of the translated linear strand of amino acids into a fully functional three-dimensional protein, is one of the most complex challenges facing the cellular protein factory.

  • Special |

    On 17 12 1903, the first powered plane took off. To celebrate, we back at the early pioneers of flight, rounds up a century of aeronautical innovation and looks forward to the future of aviation.

  • Special |

    Antibodies are the researcher's Swiss army knife: there's a tool for every purpose, and they're made in more shapes and sizes than ever. Pete Moore and Julie Clayton report.

  • Nature Outlook |

    San Diego: Rise of a high-tech cluster. Natureis pleased to present a supplement on the San Diego region. The features in this supplement examine the evolution of San Diego from a small military town to a high-tech juggernaut.

  • Insight |

    The importance of fossil fuels to human society cannot be overstated. Naturally formed reservoirs of hydrocarbons occur in a variety of geological contexts (most notably as oil and gas) and are exploited to satisfy the majority of our energy needs. Such resources are finite, yet the demand for fossil fuels is growing as the industrialization of the world continues apace. The usage of fossil fuels also comes at a cost, for example, they are strongly implicated as the main driver of climate change. Consequently, the societal impact of hydrocarbons is multi-faceted, encompassing economics, politics and the environment - all issues that are the subject of ongoing and often heated public debate.

  • Special |

    Peering down an eyepiece is becoming a thing of the past. Tim Chapman takes a look into the digital world of a new generation of microscopes and imaging systems.

  • Special |

    Advanced software and services aimed at the non-bioinformatician are making it easier to ride the tidal-wave of genomics and proteomics data. Steve Buckingham reports.

  • Special |

    In a series of four dispatches, Nature's John Whitfield looks at the issues facing America's most remote state.