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The GUS reporter gene system is already a powerful tool for the assessment of gene activity in transgenic plants. Further developments may lead to routine in vivo analysis and fusion genetics.
This week's focus on recombinant DNA technology features a protocol for the rapid separation of plasmid DNA, a baculovirus expression system and customized RNA-oligos.
Addressing the problems associated with commercial instrumentation for pulsed-field gel electrophoresis, the authors describe a versatile instrument that you can assemble yourself with considerable cost savings.
A solid scintillator, low-cost spectrophotometer and a new protein/peptide sequencer will be featured at next week's Salon du Laboratoire in Paris, France.
Genetic manipulation of mammalian cells has provided a means of producing unlimited quantities of a high purity, virus-free preparation of factor VIM — the most complex protein manufactured through rDNA technology to date.
Highlights at next week's American Society for Cell Biology Annual Meeting in Houston, Texas include an interactive 3-D graphics software package and formuIin-free tissue fixative.
Efforts to alter the mAb component of pharmaceuticals have focused on making them more human-lIke and smaller. Ultimately, the smallest molecular recognition unit derived from antibodies may be a single complementarity region.
Event recording methods have evolved from stopwatches and checksheets, through chart recorders and dedicated electronic event recorders, to flexible systems based on off-the-shelf microcomputers.
Microwave-in-the-bag agarose, a scanning densitometer with zig-zag optics, and an automated DNA sequencing system are among this week's products that focus on electrophoresis.
Powerful molecular modelling software can be used to visualize the tertiary structures of biologically significant proteins, with important implications for rational drug design.
A robotic titration workstation and 3-D molecular modelling software are a selection of what next week's Scientific Computing and Automation Confer-ence in Philadelphia, Pennsylvania, has to offer.
Analytical ultracentrifugation is still the best method for quantitative studies of the interactions between macromolecules. There will soon be a modern alternative to the ancient Beckman Model E.
Visitors to British Lab Week, in London, can expect to see a wide range of laboratory products: from gel documentation systems to water purifiers that keep water particle-free.
Fluomicrospheres coated with antibodies or receptors eliminate the need to separate bound from free ligand in both radioimmunoassays and ligand-binding assays.
Buffers in tablet form, a bright-blue fluorescent fluorophore, and protein G immobilized to membranes and gels are a selection of this week's new ideas for the immunologist.
The environmental scanning electron microscope (SEM) eliminates the high-vacuum requirement of conventional SEM, allowing the analysis of unprepared, wet samples.
Atroubleshooting modem linkfor EM hardware and a high-sensitivity imaging plate for TEMs are a few of the new ideas for microscopy that can be seen at EMAG-MICRO '89 in London next week.
