Outlook in 2016

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  • The symptoms of Crohn's disease and ulcerative colitis, the two main forms of inflammatory bowel disease (IBD), can be severe and lifelong. And the condition is becoming increasingly common worldwide.

    • Michael Eisenstein
    Outlook
  • Many people with inflammatory bowel disease (IBD) also have mental health issues. Eva Szigethy, a psychiatrist at the University of Pittsburgh in Pennsylvania, studies how cognitive therapy can help people with gastrointestinal problems. She spoke to Nature about the relationship between mental health and IBD.

    • Neil Savage
    Outlook
  • Helminths are worms that can live in the human intestine. Joel Weinstock, a gastroenterologist at Tufts Medical Center in Boston, Massachusetts, studies how they affect inflammation and the body's immune response. He spoke to Nature about how helminths might lead to treatments for inflammatory bowel disease (IBD).

    • Neil Savage
    Outlook
  • Gene exploration is providing unexpected insights into inflammatory bowel disease, and getting scientists closer to finding treatments that target the biological mechanisms.

    • Sarah DeWeerdt
    Outlook
  • Four regenerative and immune-system therapies taking on the toughest cases of inflammatory bowel disease.

    • Eric Bender
    Outlook
  • Inflammatory bowel disease is a growing problem in Asia. But that increase presents a golden opportunity for research.

    • Kelly Rae Chi
    Outlook
  • Transplants of faecal matter have done wonders for the treatment of certain gastrointestinal infections. Will they ever work for inflammatory bowel disease?

    • Liam Drew
    Outlook
  • Advances in technology have outpaced our understanding of organ development and injury response. It's time to reassess, says Stephen Badylak.

    • Stephen Badylak
    Outlook
  • For centuries, scientists have been captivated by the phenomenal feats of regeneration found in nature. Despite decades of research, attempts to replace or repair parts of the human body have met with only modest success. Fresh understanding of organ formation coupled with new technologies may help to unlock long-sought cures.

    • Cassandra Willyard
    Outlook
  • Stem-cell therapy promises to restore motor function after a stroke or spinal-cord injury, but neurologists are proceeding with caution.

    • Katherine Bourzac
    Outlook
  • Adult stem cells have become a regulatory battleground as clinicians, scientists and ethicists debate whether the road to the clinic should be shorter.

    • Michael Eisenstein
    Outlook
  • Multiple sclerosis often strikes between the ages of 20 and 40, when people are entering the workforce and raising families.

    • Charles Schmidt
    Outlook
  • Dietary changes may be able to alleviate the symptoms of multiple sclerosis, but testing the effects of diet will need a different protocol to the one used for drugs.

    • Sujata Gupta
    Outlook
  • It is time for a bolder approach to developing drugs for progressive multiple sclerosis, says Bibi Bielekova.

    • Bibi Bielekova
    Outlook