Letters

  • Letter |

    Species comparisons using single-cell transcriptomics and accessible chromatin profiling in stem cell-derived cerebral organoids are used to map dynamic gene-regulatory changes that are unique to humans.

    • Sabina Kanton
    • , Michael James Boyle
    • , Zhisong He
    • , Malgorzata Santel
    • , Anne Weigert
    • , Fátima Sanchís-Calleja
    • , Patricia Guijarro
    • , Leila Sidow
    • , Jonas Simon Fleck
    • , Dingding Han
    • , Zhengzong Qian
    • , Michael Heide
    • , Wieland B. Huttner
    • , Philipp Khaitovich
    • , Svante Pääbo
    • , Barbara Treutlein
    •  & J. Gray Camp
  • Letter |

    Widespread formation of new particles from condensable vapours observed in the tropical upper troposphere is an important source of cloud condensation nuclei in the lower troposphere, affecting cloud properties.

    • Christina J. Williamson
    • , Agnieszka Kupc
    • , Duncan Axisa
    • , Kelsey R. Bilsback
    • , ThaoPaul Bui
    • , Pedro Campuzano-Jost
    • , Maximilian Dollner
    • , Karl D. Froyd
    • , Anna L. Hodshire
    • , Jose L. Jimenez
    • , John K. Kodros
    • , Gan Luo
    • , Daniel M. Murphy
    • , Benjamin A. Nault
    • , Eric A. Ray
    • , Bernadett Weinzierl
    • , James C. Wilson
    • , Fangqun Yu
    • , Pengfei Yu
    • , Jeffrey R. Pierce
    •  & Charles A. Brock
  • Letter |

    Three-dimensional gas velocities in the gapped disk around the young star HD 163296 show meridional flows from the surface of the disk towards its midplane at gap locations.

    • Richard Teague
    • , Jaehan Bae
    •  & Edwin A. Bergin
  • Letter |

    A genetically encoded fluorescent voltage indicator, SomArchon, is used to image changes in membrane voltage from many neurons simultaneously in multiple brain regions of awake, behaving mice.

    • Kiryl D. Piatkevich
    • , Seth Bensussen
    • , Hua-an Tseng
    • , Sanaya N. Shroff
    • , Violeta Gisselle Lopez-Huerta
    • , Demian Park
    • , Erica E. Jung
    • , Or A. Shemesh
    • , Christoph Straub
    • , Howard J. Gritton
    • , Michael F. Romano
    • , Emma Costa
    • , Bernardo L. Sabatini
    • , Zhanyan Fu
    • , Edward S. Boyden
    •  & Xue Han
  • Letter |

    The histidine–aspartate kinase Sln1 acts as a molecular sensor of turgor in appressoria of the rice blast fungus Magnaporthe oryzae, enabling penetration of the host leaf cuticle and plant infection.

    • Lauren S. Ryder
    • , Yasin F. Dagdas
    • , Michael J. Kershaw
    • , Chandrasekhar Venkataraman
    • , Anotida Madzvamuse
    • , Xia Yan
    • , Neftaly Cruz-Mireles
    • , Darren M. Soanes
    • , Miriam Oses-Ruiz
    • , Vanessa Styles
    • , Jan Sklenar
    • , Frank L. H. Menke
    •  & Nicholas J. Talbot
  • Letter |

    A six-coordinate transition-metal complex with a hexagonal planar geometry is isolated and characterized.

    • Martí Garçon
    • , Clare Bakewell
    • , George A. Sackman
    • , Andrew J. P. White
    • , Richard I. Cooper
    • , Alison J. Edwards
    •  & Mark R. Crimmin
  • Letter |

    Characterization of a capillary flow phenomenon termed self-coalescence leads to the development of scalable, compact microfluidic devices that could see application in diagnostics, high-throughput screening and biological assays.

    • Onur Gökçe
    • , Samuel Castonguay
    • , Yuksel Temiz
    • , Thomas Gervais
    •  & Emmanuel Delamarche
  • Letter |

    An analogue quantum simulator based on ultracold atoms in optical lattices and cavity quantum electrodynamics is proposed for the solution of quantum chemistry problems and tested numerically for a simple molecule.

    • Javier Argüello-Luengo
    • , Alejandro González-Tudela
    • , Tao Shi
    • , Peter Zoller
    •  & J. Ignacio Cirac
  • Letter |

    Simulated mergers of two massive stars provide a solution to the long-standing puzzle of the origin of strong magnetic fields in a subset of massive stars.

    • Fabian R. N. Schneider
    • , Sebastian T. Ohlmann
    • , Philipp Podsiadlowski
    • , Friedrich K. Röpke
    • , Steven A. Balbus
    • , Rüdiger Pakmor
    •  & Volker Springel
  • Letter |

    A range of SF3B1 mutations promote tumorigenesis through the repression of BRD9, a core component of the non-canonical BAF complex, and correcting BRD9 mis-splicing in these SF3B1-mutant cells suppresses tumour growth.

    • Daichi Inoue
    • , Guo-Liang Chew
    • , Bo Liu
    • , Brittany C. Michel
    • , Joseph Pangallo
    • , Andrew R. D’Avino
    • , Tyler Hitchman
    • , Khrystyna North
    • , Stanley Chun-Wei Lee
    • , Lillian Bitner
    • , Ariele Block
    • , Amanda R. Moore
    • , Akihide Yoshimi
    • , Luisa Escobar-Hoyos
    • , Hana Cho
    • , Alex Penson
    • , Sydney X. Lu
    • , Justin Taylor
    • , Yu Chen
    • , Cigall Kadoch
    • , Omar Abdel-Wahab
    •  & Robert K. Bradley
  • Letter |

    In high-entropy alloys, atomic-resolution chemical mapping shows that swapping some of the atoms for larger, more electronegative elements results in atomic-scale modulations that produce higher yield strength, excellent strain hardening and ductility.

    • Qingqing Ding
    • , Yin Zhang
    • , Xiao Chen
    • , Xiaoqian Fu
    • , Dengke Chen
    • , Sijing Chen
    • , Lin Gu
    • , Fei Wei
    • , Hongbin Bei
    • , Yanfei Gao
    • , Minru Wen
    • , Jixue Li
    • , Ze Zhang
    • , Ting Zhu
    • , Robert O. Ritchie
    •  & Qian Yu
  • Letter |

    A ‘click’ reaction is developed for the simple and rapid formation of azides from primary amines, and is used to prepare a library of over 1,200 azides for subsequent use in the existing triazole annulation click reaction.

    • Genyi Meng
    • , Taijie Guo
    • , Tiancheng Ma
    • , Jiong Zhang
    • , Yucheng Shen
    • , Karl Barry Sharpless
    •  & Jiajia Dong
  • Letter |

    In humans and mouse models, the mycobiome of pancreatic ductal adenocarcinoma tumours is markedly enriched in Malassezia species compared to that of normal pancreas, which implicates these pathogenic fungi in oncogenesis.

    • Berk Aykut
    • , Smruti Pushalkar
    • , Ruonan Chen
    • , Qianhao Li
    • , Raquel Abengozar
    • , Jacqueline I. Kim
    • , Sorin A. Shadaloey
    • , Dongling Wu
    • , Pamela Preiss
    • , Narendra Verma
    • , Yuqi Guo
    • , Anjana Saxena
    • , Mridula Vardhan
    • , Brian Diskin
    • , Wei Wang
    • , Joshua Leinwand
    • , Emma Kurz
    • , Juan A. Kochen Rossi
    • , Mautin Hundeyin
    • , Constantinos Zambrinis
    • , Xin Li
    • , Deepak Saxena
    •  & George Miller
  • Letter |

    Signalling between the transcription factor IRF6 and the kinase RIPK4, in particular the phosphorylation of IRF6 by RIPK4, regulates epidermal differentiation and lipid metabolism, thereby maintaining the function of the epidermal barrier.

    • Nina Oberbeck
    • , Victoria C. Pham
    • , Joshua D. Webster
    • , Rohit Reja
    • , Christine S. Huang
    • , Yue Zhang
    • , Merone Roose-Girma
    • , Søren Warming
    • , Qingling Li
    • , Andrew Birnberg
    • , Weng Wong
    • , Wendy Sandoval
    • , László G. Kőműves
    • , Kebing Yu
    • , Debra L. Dugger
    • , Allie Maltzman
    • , Kim Newton
    •  & Vishva M. Dixit
  • Letter |

    Aerial sampling in the Sahel of Mali reveals large numbers of windborne malaria mosquitoes that had recently fed on blood and could cover hundreds of kilometres in a single night.

    • Diana L. Huestis
    • , Adama Dao
    • , Moussa Diallo
    • , Zana L. Sanogo
    • , Djibril Samake
    • , Alpha S. Yaro
    • , Yossi Ousman
    • , Yvonne-Marie Linton
    • , Asha Krishna
    • , Laura Veru
    • , Benjamin J. Krajacich
    • , Roy Faiman
    • , Jenna Florio
    • , Jason W. Chapman
    • , Don R. Reynolds
    • , David Weetman
    • , Reed Mitchell
    • , Martin J. Donnelly
    • , Elijah Talamas
    • , Lourdes Chamorro
    • , Ehud Strobach
    •  & Tovi Lehmann
  • Letter |

    CRISPR–Cas9 engineering of the Drosophila Atpα gene (encoding the α-subunit of the sodium pump) is used to study the ability of mutations that evolved independently in several insect orders to confer resistance to keystone plant toxins.

    • Marianthi Karageorgi
    • , Simon C. Groen
    • , Fidan Sumbul
    • , Julianne N. Pelaez
    • , Kirsten I. Verster
    • , Jessica M. Aguilar
    • , Amy P. Hastings
    • , Susan L. Bernstein
    • , Teruyuki Matsunaga
    • , Michael Astourian
    • , Geno Guerra
    • , Felix Rico
    • , Susanne Dobler
    • , Anurag A. Agrawal
    •  & Noah K. Whiteman
  • Letter |

    Analyses of transcriptomes from patients with acute myeloid leukaemia identified frequently co-occurring mutations of IDH2 and SRSF2, which functional analyses showed to have distinct and coordinated leukaemogenic effects on the epigenome and RNA splicing.

    • Akihide Yoshimi
    • , Kuan-Ting Lin
    • , Daniel H. Wiseman
    • , Mohammad Alinoor Rahman
    • , Alessandro Pastore
    • , Bo Wang
    • , Stanley Chun-Wei Lee
    • , Jean-Baptiste Micol
    • , Xiao Jing Zhang
    • , Stephane de Botton
    • , Virginie Penard-Lacronique
    • , Eytan M. Stein
    • , Hana Cho
    • , Rachel E. Miles
    • , Daichi Inoue
    • , Todd R. Albrecht
    • , Tim C. P. Somervaille
    • , Kiran Batta
    • , Fabio Amaral
    • , Fabrizio Simeoni
    • , Deepti P. Wilks
    • , Catherine Cargo
    • , Andrew M. Intlekofer
    • , Ross L. Levine
    • , Heidi Dvinge
    • , Robert K. Bradley
    • , Eric J. Wagner
    • , Adrian R. Krainer
    •  & Omar Abdel-Wahab
  • Letter |

    Cryo-electron microscopy structures of the Saccharomyces cerevisiae inner kinetochore complex provide insights into the interdependencies of constituent subcomplexes and the mechanism of centromeric nucleosome recognition.

    • Kaige Yan
    • , Jing Yang
    • , Ziguo Zhang
    • , Stephen H. McLaughlin
    • , Leifu Chang
    • , Domenico Fasci
    • , Ann E. Ehrenhofer-Murray
    • , Albert J. R. Heck
    •  & David Barford
  • Letter |

    CDC7 inhibition selectively induces senescence in hepatocellular carcinoma cells with TP53 mutations, which enables the selective apoptotic cell death of these senescent cells using inhibitors of mTOR signalling.

    • Cun Wang
    • , Serena Vegna
    • , Haojie Jin
    • , Bente Benedict
    • , Cor Lieftink
    • , Christel Ramirez
    • , Rodrigo Leite de Oliveira
    • , Ben Morris
    • , Jules Gadiot
    • , Wei Wang
    • , Aimée du Chatinier
    • , Liqin Wang
    • , Dongmei Gao
    • , Bastiaan Evers
    • , Guangzhi Jin
    • , Zheng Xue
    • , Arnout Schepers
    • , Fleur Jochems
    • , Antonio Mulero Sanchez
    • , Sara Mainardi
    • , Hein te Riele
    • , Roderick L. Beijersbergen
    • , Wenxin Qin
    • , Leila Akkari
    •  & René Bernards
  • Letter |

    Estimates for when critical environmental streamflow limits will be reached—with potentially devastating economic and environmental effects—are obtained using a global model that links groundwater pumping with the groundwater flow to rivers.

    • Inge E. M. de Graaf
    • , Tom Gleeson
    • , L. P. H. (Rens) van Beek
    • , Edwin H. Sutanudjaja
    •  & Marc F. P. Bierkens
  • Letter |

    Tadpoles of strawberry poison frogs (Oophaga pumilio) are shown to imprint on adult coloration, affecting both male aggression biases and female preferences and setting the stage for speciation by sexual selection.

    • Yusan Yang
    • , Maria R. Servedio
    •  & Corinne L. Richards-Zawacki
  • Letter |

    Sea level varied by 13 ± 5 metres on average, but up to 25 metres, over glacial–interglacial cycles during the Pliocene epoch, due to partial collapses of Antarctic Ice Sheets.

    • G. R. Grant
    • , T. R. Naish
    • , G. B. Dunbar
    • , P. Stocchi
    • , M. A. Kominz
    • , P. J. J. Kamp
    • , C. A. Tapia
    • , R. M. McKay
    • , R. H. Levy
    •  & M. O. Patterson
  • Letter |

    There are two distinct kinematic populations of globular clusters in Messier 31 (M31, the Andromeda galaxy) with rotation axes perpendicular to each other, suggesting that they arose from merger events separated by billions of years.

    • Dougal Mackey
    • , Geraint F. Lewis
    • , Brendon J. Brewer
    • , Annette M. N. Ferguson
    • , Jovan Veljanoski
    • , Avon P. Huxor
    • , Michelle L. M. Collins
    • , Patrick Côté
    • , Rodrigo A. Ibata
    • , Mike J. Irwin
    • , Nicolas Martin
    • , Alan W. McConnachie
    • , Jorge Peñarrubia
    • , Nial Tanvir
    •  & Zhen Wan
  • Letter |

    Clinical benefit was observed in 34% of a cohort of 215 patients with cancer who received treatment with anticancer drugs outside of their approved label, in the Drug Rediscovery protocol trial.

    • D. L. van der Velden
    • , L. R. Hoes
    • , H. van der Wijngaart
    • , J. M. van Berge Henegouwen
    • , E. van Werkhoven
    • , P. Roepman
    • , R. L. Schilsky
    • , W. W. J. de Leng
    • , A. D. R. Huitema
    • , B. Nuijen
    • , P. M. Nederlof
    • , C. M. L. van Herpen
    • , D. J. A. de Groot
    • , L. A. Devriese
    • , A. Hoeben
    • , M. J. A. de Jonge
    • , M. Chalabi
    • , E. F. Smit
    • , A. J. de Langen
    • , N. Mehra
    • , M. Labots
    • , E. Kapiteijn
    • , S. Sleijfer
    • , E. Cuppen
    • , H. M. W. Verheul
    • , H. Gelderblom
    •  & E. E. Voest
  • Letter |

    An analysis of the B cell receptor repertoire in six immune-mediated diseases reveals that there are substantial differences in clonality, isotype use, class switching and use of the IGHV genes between diseases.

    • R. J. M. Bashford-Rogers
    • , L. Bergamaschi
    • , E. F. McKinney
    • , D. C. Pombal
    • , F. Mescia
    • , J. C. Lee
    • , D. C. Thomas
    • , S. M. Flint
    • , P. Kellam
    • , D. R. W. Jayne
    • , P. A. Lyons
    •  & K. G. C. Smith
  • Letter |

    PdMo bimetallene, a highly curved and sub-nanometre-thick nanosheet of a palladium–molybdenum alloy, is an efficient and stable electrocatalyst for the oxygen reduction and evolution reactions under alkaline conditions.

    • Mingchuan Luo
    • , Zhonglong Zhao
    • , Yelong Zhang
    • , Yingjun Sun
    • , Yi Xing
    • , Fan Lv
    • , Yong Yang
    • , Xu Zhang
    • , Sooyeon Hwang
    • , Yingnan Qin
    • , Jing-Yuan Ma
    • , Fei Lin
    • , Dong Su
    • , Gang Lu
    •  & Shaojun Guo
  • Letter |

    After the Cretaceous/Palaeogene mass extinction event, nannoplankton communities exhibited volatility for 1.8 million years before a more stable community emerged, coinciding with restoration of the carbon cycle and a fully functioning biological pump between the surface and deep sea.

    • Sarah A. Alvarez
    • , Samantha J. Gibbs
    • , Paul R. Bown
    • , Hojung Kim
    • , Rosie M. Sheward
    •  & Andy Ridgwell
  • Letter |

    Juxtaposition of region-specific gut spheroids derived from human pluripotent stem cells in the absence of extrinsic factors results in development of segregated hepato-biliary-pancreatic anlages that recapitulate early morphogenetic events.

    • Hiroyuki Koike
    • , Kentaro Iwasawa
    • , Rie Ouchi
    • , Mari Maezawa
    • , Kirsten Giesbrecht
    • , Norikazu Saiki
    • , Autumn Ferguson
    • , Masaki Kimura
    • , Wendy L. Thompson
    • , James M. Wells
    • , Aaron M. Zorn
    •  & Takanori Takebe
  • Letter |

    Globally distributed kimberlites have their origins in a single, homogeneous early Earth reservoir that was subsequently perturbed, probably by subduction along the margins of Pangaea, around 200 million years ago.

    • Jon Woodhead
    • , Janet Hergt
    • , Andrea Giuliani
    • , Roland Maas
    • , David Phillips
    • , D. Graham Pearson
    •  & Geoff Nowell
  • Letter |

    X-ray diffraction measurements of solid hydrogen provide crystallographic information for high-pressure phases of hydrogen and transitions between them, suggesting a series of isostructural transitions under compression before band closure and metallization.

    • Cheng Ji
    • , Bing Li
    • , Wenjun Liu
    • , Jesse S. Smith
    • , Arnab Majumdar
    • , Wei Luo
    • , Rajeev Ahuja
    • , Jinfu Shu
    • , Junyue Wang
    • , Stanislav Sinogeikin
    • , Yue Meng
    • , Vitali B. Prakapenka
    • , Eran Greenberg
    • , Ruqing Xu
    • , Xianrong Huang
    • , Wenge Yang
    • , Guoyin Shen
    • , Wendy L. Mao
    •  & Ho-Kwang Mao
  • Letter |

    A crystal structure of Thermoplasmatales archaeon heliorhodopsin at 2.4 Å resolution shows that it adopts a similar fold to that of type I rhodopsin—despite the low sequence identity—but there are also several marked differences that provide insights into heliorhodopsin function.

    • Wataru Shihoya
    • , Keiichi Inoue
    • , Manish Singh
    • , Masae Konno
    • , Shoko Hososhima
    • , Keitaro Yamashita
    • , Kento Ikeda
    • , Akimitsu Higuchi
    • , Tamaki Izume
    • , Sae Okazaki
    • , Masanori Hashimoto
    • , Ritsu Mizutori
    • , Sahoko Tomida
    • , Yumeka Yamauchi
    • , Rei Abe-Yoshizumi
    • , Kota Katayama
    • , Satoshi P. Tsunoda
    • , Mikihiro Shibata
    • , Yuji Furutani
    • , Alina Pushkarev
    • , Oded Béjà
    • , Takayuki Uchihashi
    • , Hideki Kandori
    •  & Osamu Nureki
  • Letter |

    FHL1 is a key factor expressed by humans and mice that is required for chikungunya virus infection and is therefore a promising target for the development of therapies against chikungunya virus.

    • Laurent Meertens
    • , Mohamed Lamine Hafirassou
    • , Thérèse Couderc
    • , Lucie Bonnet-Madin
    • , Vasiliya Kril
    • , Beate M. Kümmerer
    • , Athena Labeau
    • , Alexis Brugier
    • , Etienne Simon-Loriere
    • , Julien Burlaud-Gaillard
    • , Cécile Doyen
    • , Laura Pezzi
    • , Thibaud Goupil
    • , Sophia Rafasse
    • , Pierre-Olivier Vidalain
    • , Anne Bertrand-Legout
    • , Lucie Gueneau
    • , Raul Juntas-Morales
    • , Rabah Ben Yaou
    • , Gisèle Bonne
    • , Xavier de Lamballerie
    • , Monsef Benkirane
    • , Philippe Roingeard
    • , Constance Delaugerre
    • , Marc Lecuit
    •  & Ali Amara
  • Letter |

    Transmission of single-spin and entangled quantum states without the physical displacement of electrons is demonstrated in a quadruple quantum dot array using the Heisenberg exchange interaction and coherent SWAP gates.

    • Yadav P. Kandel
    • , Haifeng Qiao
    • , Saeed Fallahi
    • , Geoffrey C. Gardner
    • , Michael J. Manfra
    •  & John M. Nichol
  • Letter |

    Nutrient content analyses of marine finfish and current fisheries landings show that fish have the potential to substantially contribute to global food and nutrition security by alleviating micronutrient deficiencies in regions where they are prevalent.

    • Christina C. Hicks
    • , Philippa J. Cohen
    • , Nicholas A. J. Graham
    • , Kirsty L. Nash
    • , Edward H. Allison
    • , Coralie D’Lima
    • , David J. Mills
    • , Matthew Roscher
    • , Shakuntala H. Thilsted
    • , Andrew L. Thorne-Lyman
    •  & M. Aaron MacNeil
  • Letter |

    17O nuclear magnetic resonance measurements on Sr2RuO4 reveal a drop of the Knight shift in the superconducting state, contradicting previous work and imposing tight constraints on the order parameter symmetry of the system.

    • A. Pustogow
    • , Yongkang Luo
    • , A. Chronister
    • , Y.-S. Su
    • , D. A. Sokolov
    • , F. Jerzembeck
    • , A. P. Mackenzie
    • , C. W. Hicks
    • , N. Kikugawa
    • , S. Raghu
    • , E. D. Bauer
    •  & S. E. Brown
  • Letter |

    A probabilistic computer utilizing probabilistic bits, or p-bits, is implemented with stochastic nanomagnetic devices in a neural-network-inspired electrical circuit operating at room temperature and demonstrates integer factorization up to 945.

    • William A. Borders
    • , Ahmed Z. Pervaiz
    • , Shunsuke Fukami
    • , Kerem Y. Camsari
    • , Hideo Ohno
    •  & Supriyo Datta
  • Letter |

    Circadian circuits, entrained by light and tuned by the brain, regulate intestinal group 3 innate lymphoid cells in mice, along with epithelial reactivity, microbiome composition and lipid metabolism.

    • Cristina Godinho-Silva
    • , Rita G. Domingues
    • , Miguel Rendas
    • , Bruno Raposo
    • , Hélder Ribeiro
    • , Joaquim Alves da Silva
    • , Ana Vieira
    • , Rui M. Costa
    • , Nuno L. Barbosa-Morais
    • , Tânia Carvalho
    •  & Henrique Veiga-Fernandes
  • Letter |

    Single-molecule dynamics reveal that the GTPase activity of eukaryotic initiation factor eIF5B serves as a kinetic checkpoint for the transition from translation initiation to elongation.

    • Jinfan Wang
    • , Alex G. Johnson
    • , Christopher P. Lapointe
    • , Junhong Choi
    • , Arjun Prabhakar
    • , Dong-Hua Chen
    • , Alexey N. Petrov
    •  & Joseph D. Puglisi
  • Letter |

    Wilderness areas with minimal levels of human disturbance promote the persistence of biodiversity by acting as buffers against species loss, and therefore represent key targets for environmental protection.

    • Moreno Di Marco
    • , Simon Ferrier
    • , Tom D. Harwood
    • , Andrew J. Hoskins
    •  & James E. M. Watson
  • Letter |

    Structural and biophysical studies reveal that low-barrier hydrogen bonds enable long-range communication between the active sites of multimeric enzymes and synchronise catalysis.

    • Shaobo Dai
    • , Lisa-Marie Funk
    • , Fabian Rabe von Pappenheim
    • , Viktor Sautner
    • , Mirko Paulikat
    • , Benjamin Schröder
    • , Jon Uranga
    • , Ricardo A. Mata
    •  & Kai Tittmann
  • Letter |

    Restoring the function of p53 in a mouse model of pancreatic ductal adenocarcinoma leads to the accumulation of α-ketoglutarate, which increases levels of the 5-hydroxymethylcytosine chromatin modification and results in reduced tumour-cell fitness.

    • John P. Morris IV
    • , Jossie J. Yashinskie
    • , Richard Koche
    • , Rohit Chandwani
    • , Sha Tian
    • , Chi-Chao Chen
    • , Timour Baslan
    • , Zoran S. Marinkovic
    • , Francisco J. Sánchez-Rivera
    • , Steven D. Leach
    • , Carlos Carmona-Fontaine
    • , Craig B. Thompson
    • , Lydia W. S. Finley
    •  & Scott W. Lowe
  • Letter |

    Observations and regional climate models show that the increasing coverage of ice slabs on the Greenland ice sheet could lead to a global sea-level rise of up to 74 millimetres by 2100.

    • M. MacFerrin
    • , H. Machguth
    • , D. van As
    • , C. Charalampidis
    • , C. M. Stevens
    • , A. Heilig
    • , B. Vandecrux
    • , P. L. Langen
    • , R. Mottram
    • , X. Fettweis
    • , M. R. van den Broeke
    • , W. T. Pfeffer
    • , M. S. Moussavi
    •  & W. Abdalati
  • Letter |

    A statistical forecast model using a deep-learning approach produces useful forecasts of El Niño/Southern Oscillation events with lead times of up to one and a half years.

    • Yoo-Geun Ham
    • , Jeong-Hwan Kim
    •  & Jing-Jia Luo