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Increased melting of ice in Greenland and Antarctica, measured by satellite gravity, has decreased the angular velocity of Earth more rapidly than before and has already affected global timekeeping.
Experiments in mouse models show that NaV1.8+ nociceptors innervate sites of injury and provide wound repair signals to immune cells by releasing calcitonin gene-related peptide (CGRP).
Learning results in persistent double-stranded DNA breaks, nuclear rupture and release of DNA fragments and histones within hippocampal CA1 neurons that, following TLR9-mediated DNA damage repair, results in their recruitment to memory circuits.
The conserved HEAT repeat protein HPO-27 is identified as a lysosome scission factor in Caenorhabditis elegans, and the human homologue MROH1 also serves the same function to maintain lysosomal homeostasis.
The strength of the Antarctic Circumpolar Current, as traced in sediment cores from the Pacific Southern Ocean, shows no linear long-term trend over the past 5.3 Myr; instead, the strongest flow occurs consistently in warmer-than-present intervals.
Anti-TRBC1 antibody–drug conjugates may offer a more potent T cell cancer therapy by bypassing the fratricide that may be limiting the efficacy of anti-TRBC1 CAR T cells in the clinical trial for patients with T cell cancers.
Antibody-mediated depletion of myeloid-biased haematopoietic stem cells in aged mice restores characteristic features of a more youthful immune system.
A study presents two cryo-EM structures of yeast Pol II pre-termination transcription complexes bound to Rat1–Rai1, and provides the mechanisms for termination of mRNA transcription in yeast and other eukaryotes.
The helicity of light from a light-emitting diode can be electrically controlled by spin–orbit torque effects, enabling a seamless integration of magnetization dynamics with photonics.
A strategy for the transfer-free direct growth of ultralong, high-quality graphene nanoribbons, which have desirable electronic properties, between layers of a boron nitride insulator is reported.
We build a polyploid reference genome for hybrid sugarcane cultivar R570, improving on its current ‘mosaic monoploid’ representation, enabling fine-grain description of genome architecture and the exploration of candidate genes underlying the Bru1 brown rust resistance locus.
DCAF5 has a quality-control function for SWI/SNF complexes and promotes the degradation of incompletely assembled SWI/SNF complexes in the absence of SMARCB1.
An analysis of the rate at which isotherms are shifting in mountain regions worldwide identifies 17 key regions with particularly high vertical isotherm shift velocities, and provides insight into how these shifts affect species ranges.
This study presents an approach to deal with spatial, temporal and phylogenetic non-independence in large-scale analyses of biodiversity change, improving trend estimation and inference across scales.
Using ultraviolet data as well as a comprehensive set of further multiwavelength observations of the supernova 2023ixf, a reliable bolometric light curve is derived that indicates the heating nature of the early emission.
We introduce multinucleic acid interaction mapping in single cells (MUSIC), for concurrent profiling of multiplex chromatin interactions, gene expression and RNA–chromatin associations within individual nuclei, as a tool for exploring chromatin architecture and transcription.
A 16-year dataset of abundance patterns of a diverse assemblage of bees in New Mexico, USA predicts declines for many bee species and indicates that drought-tolerant taxa will prevail in a warming and drying climate.