Product Review

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  • The detection and characterization of mutations in genes has become a major area of interest in many areas of biology. Such variation may account for speciation, tumour formation, drug resistance, as well as the more obvious nature of inherited disease.

    • R. G. H. Cotton
    • A. D. B. Malcolm
    Product Review
  • About 450 exhibitors from 20 countries are expected to attend Biotechnica '91, the International Trade Fair for Biotechnology that is to be held 22–24 October in Hannover, Germany. A new gel capillary for capillary electrophoresis and an inverted confocal microscope are among the exhibits.

    Product Review
  • A new substrate for the growth of anchorage-dependent cells and a closed perfusion chamber that provides the right environment for making single-cell fluorescence measurements — new tools and tips for cell and tissue culture.

    • Diane Gershon
    Product Review
  • Next week's American Chemical Society meeting to be held in New York City will feature an automated peptide synthesizer based on a proprietary dry-activation FMOC chemistry, a mass analyser for molecular weight determination from picomole amounts, and an NMR software module.

    • Diane Gershon
    Product Review
  • New technologies for multiple chemical synthesis of oligonucleotides and stepwise hybridization on a solid-phase support enable the rapid and cost-effective preparation of long duplex DNA regions. Will these new technologies usher in a new era in protein engineering?

    • Kenneth L. Beattie
    • Richard F. Fowler
    Product Review
  • A recombinant T4 gene 32 protein, antisense phosphorothioate oligos and a second generation capillary electrophoresis system with a thermostatting capability — new product ideas from the molecular biology marketplace.

    • Diane Gershon
    Product Review
  • A human and bovine serum alternative and a microbalance that cuts down on unwanted temperature fluctuations and vibrations by separating the weighing cell from the control unit — new product news from Switzerland.

    Product Review
  • Building upon earlier studies with fluorescent probes, the authors describe a new cell tracking compound, PKH95, with a radioactive signal, which has been developed specifically for high-sensitivity cell tracking and biodistribution studies.

    • Sue E. Slezak
    • Katharine A. Muirhead
    Product Review
  • This week's labelling technology product line-up includes reagents for three-colour cell analysis kits, for end-labelling oligos and an ethidium bromide stain substitute.

    • Diane Gershon
    Product Review
  • An automated DNA sequencing system, the collaborative effort of Japanese scientists and engineers, which has a potential output of up to 108,000 bases per day is described.

    • Isao Endo
    • Eiichi Soeda
    • Katsuo Nishi
    Product Review
  • Handy helpers in this week's issue include a dual-purpose device for vertical electrophoresis and electroblotting, a triple-tray gel box and news of a new patent sequence data bank.

    • Diane Gershon
    Product Review
  • By combining small colloidal gold probes with video-enhanced quantitative microscopy, the intracellular dynamics of specific proteins in living cells can now be studied.

    • Hugo Geerts
    • Mark de Brabander
    • Rony Nuydens
    Product Review
  • Focusingthisweekon microscopy and image analysis, new products include a hand-held microscope, a new objective that converts a standard microscope to a fluorescence microscope, and a DNA sequence gel reader with voice recognition.

    Product Review
  • Stock up your shelves with the latest biochemicals and reagents to come off the production line, including new phage lambda cloning vectors, a genetically-engineered substrate for receptor-specific mammalian cell attachment, and a kit for detecting Mycoplasma contamination in cell lines.

    Product Review
  • Protein engineering has made it possible to combine the binding sites of murine antibodies with human antibody regions. Antibodies constructed in this way have important advantages for therapy.

    • Man Sung Co
    • Cary Queen
    Product Review
  • Neuropeptide Y antiserum for immunohistochemical use, a monoclonal antibody to cytokeratin 20 and a range of fluorescent microspheres for antibody attachment – new products for today's immunologist.

    • Diane Gershon
    Product Review
  • A membrane-based filtration system, designed for use in the production of biotherapeutics, predictably removes viruses as a function of size.

    • Anthony J. DiLeo
    • Anthony E. Allegrezza Jr
    Product Review