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The detection and characterization of mutations in genes has become a major area of interest in many areas of biology. Such variation may account for speciation, tumour formation, drug resistance, as well as the more obvious nature of inherited disease.
About 450 exhibitors from 20 countries are expected to attend Biotechnica '91, the International Trade Fair for Biotechnology that is to be held 22–24 October in Hannover, Germany. A new gel capillary for capillary electrophoresis and an inverted confocal microscope are among the exhibits.
A new substrate for the growth of anchorage-dependent cells and a closed perfusion chamber that provides the right environment for making single-cell fluorescence measurements — new tools and tips for cell and tissue culture.
Next week's American Chemical Society meeting to be held in New York City will feature an automated peptide synthesizer based on a proprietary dry-activation FMOC chemistry, a mass analyser for molecular weight determination from picomole amounts, and an NMR software module.
New technologies for multiple chemical synthesis of oligonucleotides and stepwise hybridization on a solid-phase support enable the rapid and cost-effective preparation of long duplex DNA regions. Will these new technologies usher in a new era in protein engineering?
A recombinant T4 gene 32 protein, antisense phosphorothioate oligos and a second generation capillary electrophoresis system with a thermostatting capability — new product ideas from the molecular biology marketplace.
A human and bovine serum alternative and a microbalance that cuts down on unwanted temperature fluctuations and vibrations by separating the weighing cell from the control unit — new product news from Switzerland.
Building upon earlier studies with fluorescent probes, the authors describe a new cell tracking compound, PKH95, with a radioactive signal, which has been developed specifically for high-sensitivity cell tracking and biodistribution studies.
This week's labelling technology product line-up includes reagents for three-colour cell analysis kits, for end-labelling oligos and an ethidium bromide stain substitute.
An automated DNA sequencing system, the collaborative effort of Japanese scientists and engineers, which has a potential output of up to 108,000 bases per day is described.
Handy helpers in this week's issue include a dual-purpose device for vertical electrophoresis and electroblotting, a triple-tray gel box and news of a new patent sequence data bank.
By combining small colloidal gold probes with video-enhanced quantitative microscopy, the intracellular dynamics of specific proteins in living cells can now be studied.
Focusingthisweekon microscopy and image analysis, new products include a hand-held microscope, a new objective that converts a standard microscope to a fluorescence microscope, and a DNA sequence gel reader with voice recognition.
Stock up your shelves with the latest biochemicals and reagents to come off the production line, including new phage lambda cloning vectors, a genetically-engineered substrate for receptor-specific mammalian cell attachment, and a kit for detecting Mycoplasma contamination in cell lines.
Protein engineering has made it possible to combine the binding sites of murine antibodies with human antibody regions. Antibodies constructed in this way have important advantages for therapy.
Neuropeptide Y antiserum for immunohistochemical use, a monoclonal antibody to cytokeratin 20 and a range of fluorescent microspheres for antibody attachment – new products for today's immunologist.