That women face persistent discriminatory barriers as they pursue careers in science is conclusively documented, broadly lamented, and acknowledged even by powerful and influential perpetrators of such discrimination. The intellectual loss is incalculable when talented women leave academic science because of their refusal to sacrifice maternal aspirations to the rigid demands of the normal male-dominated pattern of career progression. A boundless loss to individuals, the educational environment, and science also results when talented women meet these traditional terms of career success, perhaps delaying or sacrificing family goals only to become bitter and resentful -- and perhaps discouraging role models for younger women with great intellectual and pedagogical potential. Yet the problem persists. No one seems to know how to get past the lamentation to sustained and constructive remedies.