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Increasing the interval between the first two mRNA-vaccine doses might boost childrens’ immunity, but it is a gamble as a new variant sweeps the globe.
Activation of the RAF protein is key to the RAS–MAPK signalling pathway, and involves the SMP protein complex. Structures for SMP shed light on the process, and suggest fresh targets for anticancer drug discovery.
In 1987, two independent groups cloned a gene that encoded the potassium-ion-channel protein Shaker, enabling functional and structural studies that have transformed ion-channel research.