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A digital model suggests the colossal ancient shark could have eaten a whale in just a few bites. Plus: how bats inspire urban design and why the Tongan volcano eruption should be a wake-up call.
The structures of single COOLAIR RNA isoforms change in abundance and shape in response to external conditions; structural mutation of these isoforms altered FLC expression and flowering time, consistent with a regulatory role of the COOLAIR structure in FLC transcription.
Analyses of newly discovered specimens of the early Cambrian microscopic animal Saccorhytus coronarius support its taxonomic classification in total-group Ecdysozoa.
Endocytosis and degradation of plasma membrane proteins in the axon initial segment, together with the diffusion-barrier mechanism, maintain a polarized distribution of plasma membrane proteins in Caenorhabditis elegans, mouse, rat and human neurons.
Multidimensional time- and angle-resolved photoelectron spectroscopy is used to determine the interlayer exciton formation process, reveal a direct hallmark of the superlattice moiré modification, and reconstruct the real-space wavefunction distribution.
CD62L+ precursors of exhausted T cells retain long-term proliferative potential, multipotency and repopulation capacity, and the transcription factor MYB is essential for the development and function of this population of cells.
A mechanism for self-oscillating pumping in a quantum gas is demonstrated using a Bose–Einstein condensate coupled to a dissipative cavity, where a particle current is observed without external periodic driving.
Live-seq, a single-cell transcriptome profiling approach that preserves cell viability during RNA extraction using fluidic force microscopy, can address a range of biological questions by transforming scRNA-seq from an end-point to a temporal analysis approach.
Analysis of a series of Earth system model experiments shows that continental rearrangement during the Phanerozoic had a marked influence on variations in ocean oxygenation, independent of atmospheric pO2.
A phase portrait study is presented that shows the chemically driven dynamics of short-lived F-actin-rich condensates that support actomyosin cortex formation.
A dynamic optimization approach using plant species data from 458 forest ecoregions suggests a strategy for when and where to conserve forests globally over the next 50 years to maximize the conservation of plant biodiversity.
Spatial-ATAC-seq—spatially resolved chromatin accessibility profiling of tissue sections using next-generation sequencing—delineated tissue-region-specific epigenetic landscapes in mouse embryos and identified gene regulators involved in the development of the central nervous system and the lymphoid tissue.