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Researchers determined the telecommunications satellite was periodically brighter than 99% of stars, and powerful X-rays have uncovered an ancient trilobite’s last meal.

Haemoglobin produced by chondrocytes forms eosin-positive haemoglobin bodies in their cytoplasm, and deletion of these bodies causes severe hypoxia.

Analysis of high-resolution annual data shows that global human settlements have expanded continuously and rapidly into flood zones, with those in the most hazardous zones increasing by 122% from 1985 to 2015.

Silicate weathering of uplifted rock depletes atmospheric CO₂, but oxidation of revealed rock organic carbon supplies CO₂, offsetting depletion to a degree dependent on regional geological history.

Assembly theory conceptualizes objects as entities defined by their possible formation histories, allowing a unified language for describing selection, evolution and the generation of novelty.

Comparisons of phenotypic and genetic association with protein levels from Icelandic and UK Biobank cohorts show that using multiple analysis platforms and stratifying populations by ancestry improves the detection of associations and allows the refinement of their location within the genome.

This study presents a continuous fossil record, extracted from a series of sediment cores, that shows how haplochromine cichlids came to dominate the fish fauna of Lake Victoria in Africa.

An orally bioavailable small-molecule active-site inhibitor of the phosphatases PTPN2 and PTPN1, ABBV-CLS-484, demonstrates immunotherapeutic efficacy in mouse models of cancer resistant to PD-1 blockade.

Although the catalogue of human protein-coding genes is nearing completion, the number of non-coding RNA genes remains highly uncertain, and for all genes much work remains to be done to understand their functions.

A set of three papers in Nature reports a new proteomics resource from the UK Biobank and initial analysis of common and rare genetic variant associations with plasma protein levels.

Binding of a sialoglycan-based primary receptor by the spike protein of the common cold human coronavirus HKU1 triggers conformational changes to a state that would allow binding to a second receptor required for cell entry.

Asynchronous flight in all major groups of insects likely arose from a single common ancestor with reversions to a synchronous flight mode enabled by shifts back and forth between different regimes in the same set of dynamic parameters.

The second Global Amphibian Assessment finds that the status of amphibians is continuing to deteriorate globally, driven predominantly by climate change, disease and habitat loss.

A high-precision, high-field test of quantum electrodynamics measuring the bound-electron g factor in hydrogen-like tin is described, which—together with state-of-the-art theory calculations—yields a stringent test in the strong-field regime.

Many different homogeneous metrics on Lie groups, which may have markedly different short-distance properties, are shown to exhibit nearly identical distance functions at long distances, suggesting a large universality class of definitions of quantum complexity.

The Pharma Proteomics Project generates the largest open-access plasma proteomics dataset to date, offering insights into trans protein quantitative trait loci across multiple biological domains, and highlighting genetic influences on ligand–receptor interactions and pathway perturbations across a diverse collection of cytokines and complement networks.

It’s only rock ’n’ roll.

Amphibians are the most vulnerable vertebrates worldwide, with 41% of species threatened with extinction. Habitat loss is the most common threat, and climate change is the main driver of increased extinction risk. Investment in amphibian conservation must be scaled up drastically and urgently to prevent further extinctions and reverse declines.

The analysis of fossils in sediment cores from Lake Victoria, Africa, reveals that a group of cichlid fish rapidly diversified as the lake got larger and provided new ecological niches, whereas the other fish there did not diversify.

Evolution by natural selection peerlessly describes how life’s complexity develops — but can it be explained in terms of physics? A new approach suggests it can.