Review, News & Views, Perspectives, Hypotheses and Analyses in 2018

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  • Observations reveal that a particular planetary nebula — the ejected envelope of an old star — is unusually enriched in rare carbon, nitrogen and oxygen isotopes. The finding could help to explain the origins of these isotopes.

    • Amanda Karakas
    News & Views
  • Some fat cells convert energy into heat, so targeting them to induce weight loss is appealing. The discovery that a subset of the cells burns glucose, rather than both glucose and lipids, could improve our ability to do just that.

    • Wenfei Sun
    • Christian Wolfrum
    News & Views
  • Almost half a century ago, it was predicted that the confinement of quantum fluctuations could induce mechanical rotation — the Casimir torque. This prediction has now been confirmed using liquid crystals.

    • Slobodan Žumer
    News & Views
  • A study in mice identifies a brain adaptation that underlies the compulsive behaviour associated with drug addiction, and which might explain why some drug users behave compulsively whereas others do not.

    • Patricia Janak
    News & Views
  • Clinical trials reveal that personalized vaccines can boost immune-cell responses to brain tumours that don’t usually respond to immunotherapy. The findings also point to how to improve such treatments.

    • Neeha Zaidi
    • Elizabeth M. Jaffee
    News & Views
  • How Nature reported a strange apparition in 1918, and the latest Christmas toys in 1968.

    News & Views
  • Some samples of human growth hormone used as therapy until the mid-1980s contain amyloid-β peptide and cause genetically modified mice to develop amyloid-β deposits in the brain.

    • Tien-Phat V. Huynh
    • David M. Holtzman
    News & Views
  • A catalytic process driven by visible light converts a mixture of mirror-image isomers of compounds called allenes to a single mirror-image isomer — opening up avenues of research for synthetic chemistry.

    • Cheng Yang
    • Yoshihisa Inoue
    News & Views
  • Many enzymatic processes involve a mechanism in which reaction intermediates are covalently attached to the enzyme’s active site. A strategy has been devised that enables mimics of these intermediates to be visualized.

    • Andrew M. Gulick
    News & Views
  • Attempts to boost the body’s antitumour immune responses can trigger a harmful inflammatory reaction called a cytokine storm. New insights into the mechanisms involved might help to prevent this problem.

    • Stanley R. RIddell
    News & Views
  • After decades of uncertainty, it now seems clear that global warming will enhance both the amplitude and the frequency of climate phenomena known as eastern Pacific El Niño events, with widespread climatic consequences.

    • Yoo-Geun Ham
    News & Views
  • How Nature reported the Apollo space missions in 1968, and a proposed aerial survey of the British Isles in 1918.

    News & Views
  • Antibodies have been engineered to recognize diverse strains of influenza, including both the A and B types of virus that cause human epidemics. Are we moving closer to achieving ‘universal’ protection against all flu strains?

    • Gary J. Nabel
    • John W. Shiver
    News & Views
  • Bacteria can use specific protein-based strategies to defend individual cells against viruses. Evidence that bacterial small molecules also target viruses provides fresh insights into how bacteria thwart viral infection.

    • Martha R. J. Clokie
    News & Views
  • A modified protocol has enabled baboons that received transplanted pig hearts to survive for more than six months. This improvement on previous efforts brings pig-to-human heart transplants a step closer.

    • Christoph Knosalla
    News & Views
  • Ammonia emissions harm humans and the environment. An analysis shows that satellites can locate sources precisely, and could thus help to monitor compliance with international agreements to limit such emissions.

    • Mark A. Sutton
    • Clare M. Howard
    News & Views
  • Magnetic materials can host a range of structures called spin textures. Two such textures — a meron and an antimeron — have been observed experimentally for the first time, in a material known as a chiral magnet.

    • Seonghoon Woo
    News & Views
  • How Nature reported innovative moving walkways in 1968, and a plea to ban gases as weapons in 1918.

    News & Views