Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
A screen utilizing an environmental DNA library in Escherichia coli is used to identify Brig1, a previously unknown anti-phage defence system with homologues across distinct clades of bacteria.
Genomic studies of Heliconius butterflies provide evidence that Heliconius elevatus is a hybrid species, and that its speciation was driven by introgression of traits from Heliconius melpomene into the other parent, an ancestor of Heliconius pardalinus.
We propose a model for a sequential, multistep activation mechanism of metabotropic glutamate receptor subtype 5, including a series of structures in lipid nanodiscs, from inactive to fully active, with agonist-bound intermediate states.
Analysis of projected sub-national damages from temperature and precipitation show an income reduction of 19% of the world economy within the next 26 years independent of future emission choices.
Challenging the belief that sympathetic ganglia are an innovation of jawed vertebrates, a study reports the presence of sympathetic neurons in an extant jawless vertebrate, the sea lamprey Petromyzon marinus.
Using observations of double-difference relocated earthquakes in a local three-dimensional velocity model for Ecuador, a detailed image of seismicity is created, forming the base for more realistic models of earthquake rupture, slip and hazard in subduction zones.
Analysis of a global dataset reveals spatiotemporal patterns of marine plankton and their biogeographical responses during climatic and environmental changes across the Cenozoic era.
A study investigates subcellular, single-cell and network-level comunication within the astrocyte network in response to the two major neurotransmitter inputs.
Near-field radiative heat transfer between two coplanar silicon carbide membranes in close proximity is enhanced by the electromagnetic corner and edge modes.
Lipopolysaccharide-induced breakdown of the blood–brain barrier requires activation of GSDMD-mediated plasma membrane permeabilization and pyroptosis in brain endothelial cells.
Analysis of the energy budget of a sample of 54 well-observed stripped-envelope supernovae of all sub-types shows statistically significant, largely model-independent, observational evidence for a non-radioactive power source in most of them.
Datasets from in situ warming experiments across 28 arctic and alpine tundra sites covering a span of less than 1 year up to 25 years show the importance of local soil conditions and warming-induced changes therein for future climatic impacts on ecosystem respiration.
Measurements of fly muscle activity using a genetically encoded calcium indicator and high-speed imaging of wing movement were used to construct a model of the insect wing hinge and the role of steering muscles in flight control.
Research published in Nature shows that surface-enhanced Raman spectroscopy carried out with colloids can quantify a range of molecules down to concentrations at the femtomolar level.
Streptomyces are discovered to produce antibacterial protein complexes that selectively inhibit the hyphal growth of related species, a function distinct from that of the small-molecule antibiotics they are known for.
The trapping of triply charged 229mTh3+ is described and its nuclear decay half-life determined, showing useful properties for the development of a nuclear clock and applications in the search for new physics.
Structures of the human calcium-sensing receptor can be bound into complex with G proteins from three different Gα subtypes while maintaining G-protein-binding specificity.
Signalling by the developmental morphogen BMP2 through the transcription factor SMAD1 has a key role in controlling the glutamatergic innervation of parvalbumin-expressing interneurons and maintaining the balance between excitation and inhibition in the mammalian cortex.