Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Volume 2 Issue 10, October 2023

Polymetallic rings by mass spectrometry

Collision-induced dissociation mass spectrometry is used to form polymetallic rings from larger, heterometallic complexes. A workflow is proposed for the topological assignment of the polymetallic rings that can be applied to structures synthesized in solution as well as in the gas phase.

See Geue et al.

Image: Hassan Tahini, ScienceBrush Design. Cover design: Amie Fernandez

Research Highlights

Top of page ⤴

News & Views

  • The activation of a Si–Si bond and its subsequent trans-addition across an alkyne substrate is a challenge. Now, a Pd-catalysed process for the trans-bis-silylation of terminal alkynes is reported, using a quinoline-substituted disilane reagent.

    • John Spencer
    News & Views
  • Cation exchange reactions convert ionic nanocrystals into new compositions through the substitution of cations. Now, a cation exchange reaction has been demonstrated on a Cu2Se nanocluster with a uniform arrangement of atoms.

    • Wonseok Lee
    • Andrew M. Smith
    News & Views
  • The conversion of CO2 into complex molecules by genetically enhanced microorganisms is desirable but challenging. Now, a two-stage strategy featuring carbon sequestration, using the cyanobacterium Synechococcus elongatus, and cellular catalysis, using Escherichia coli, is reported for the synthesis of value-added molecules from CO2.

    • Minrui Ren
    • Lennart Schada von Borzyskowski
    News & Views
  • Nearly all phosphorus-containing chemicals are prepared from phosphate ores via hazardous, energy-intensive, multi-step procedures that feature toxic, pyrophoric white phosphorus (P4) as an intermediate. Using a different approach, many of these products can be prepared from phosphates in two simple steps free from P4.

    • Daniel J. Scott
    News & Views
  • Supramolecular assemblies of peptides with differing morphologies and properties are formed by varying the synthetic route to the fibrous assemblies.

    • Brigitte A. K. Kriebisch
    • Job Boekhoven
    News & Views
Top of page ⤴


Top of page ⤴


  • Polymetallic rings are formed via the collision-induced dissociation of larger complexes. Ion mobility mass spectrometry can be used to determine whether the formed polymetallic complexes are cyclic or acyclic.

    • Niklas Geue
    • Grigore A. Timco
    • Perdita E. Barran
    Article Open Access
  • trans-Bis-silylation of alkynes is underdeveloped compared with cis-bis-silylation. Now, a Pd-catalysed method for the trans-bis-silylation of terminal alkynes is reported using disilane reagent 8-(2-substituted 1,1,2,2-tetramethyldisilanyl)quinoline to selectively form trans-bis-silylated alkenes. Mechanistic studies reveal that the reaction probably proceeds through a combined cis-bis-silylation and Z/E isomerization process.

    • Shuang Zhao
    • Yun Zhang
    • Dongbing Zhao
  • By combining coordination, cluster and colloidal chemistry, precision synthesis is realized in cation-exchange reactions of nanoclusters (Cu2Se to CdSe). The precise transformation unveils the origin of chirality and polarity in semiconductor nanomaterials and enables atomic visualization of complex reaction mechanisms.

    • Fuyan Ma
    • Khalil A. Abboud
    • Chenjie Zeng
  • Carbon-negative biomanufacturing is typically hampered by narrow product scope and light-induced decomposition. Now, an integrated photosynthetic carbon sequestration and cellular catalysis strategy for CO2 valorization are reported. Multiple gene editing and a high-throughput workflow have facilitated its application to the biocatalytic production of styrene, intracellular unstable aldehydes and photosensitive molecules from CO2.

    • Chaofeng Li
    • Lijie Yin
    • Jun Ni
  • The synthesis of phosphorous compounds in the 5+ oxidation state typically relies on energy-consuming processes using white phosphorus (P4). Now, a simple approach that cleaves P–O bonds in ubiquitous PV sources to form a PO2+ phosphorylation agent enables the redox-neutral synthesis of various PV chemicals.

    • Tobias Schneider
    • Kai Schwedtmann
    • Jan J. Weigand
  • Nature uses complex supramolecular reaction networks to regulate structure formation. Now, by creating a photolytic reaction cascade with competing redox pathways, different hierarchical assemblies can be tailored based on a single molecular identity.

    • Patrick Roth
    • Raphael Meyer
    • Tanja Weil
    Article Open Access
  • Cross-coupling reactions are among the most widely used synthetic methods in medicinal chemistry; however, they typically form bonds with C(sp2)-hybridized atoms. The resulting molecules often have suboptimal physicochemical and topological properties. Here virtual and experimental libraries of products from benzylic C(sp3)–H cross-coupling are shown to access underpopulated 3D chemical space.

    • Si-Jie Chen
    • Cyndi Qixin He
    • Shannon S. Stahl
Top of page ⤴


Quick links