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Volume 7 Issue 12, December 2022

The biointerface established by vertical nanoprobes—arrays of vertical high-aspect-ratio nanostructures—is a simple, controllable and powerful tool for interrogating and manipulating cells. The cover shows a colored electron microscopy image of a single cell on nanoneedles. See Roey Elnathan et al.

Image: Ciro Chiappini and Cong Wang. Cover design: Charlotte Gurr.

Comment

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  • Liquid metals are promising multifunctional materials, but their single-colour physical appearance limits their applicability. There are several methods to endow liquid metals with colour and fluorescence, and although breakthroughs have been made in controlling their optical and interfacial properties, more work is needed to refine the synthetic strategies, better understand the coloration effects and enable the applications of colourful liquid metals.

    • Liangfei Duan
    • Tong Zhou
    • Qingju Liu
    Comment
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Research Highlights

  • An article in Advanced Functional Materials reports a dual-functional hydrogel platform that can treat inflammation and promote bone regeneration.

    • Charlotte Allard
    In Brief
  • An article in ACS Nano presents a hydrogel with a mushroom-like shape that can block and treat gastrointestinal puncture wounds.

    • Charlotte Allard
    In Brief
  • An article in Advanced Functional Materials presents a hydrogel adhesive to treat nerve injuries.

    • Charlotte Allard
    In Brief
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Reviews

  • Hydrogels are one of the most promising materials to bridge the stark disparities between traditional machines and biological tissues for successful interfacing between humans and machines. This Review discusses the functional modes, design principles, and current and future applications of hydrogel interfaces for the merging of humans and machines.

    • Hyunwoo Yuk
    • Jingjing Wu
    • Xuanhe Zhao
    Review Article
  • Vertical nanoprobes are high-aspect-ratio nanomaterials used to manipulate and interrogate cells with high spatiotemporal resolution and limited perturbation. This Review discusses the design principles to establish effective nanoprobe biointerfaces for drug delivery, intracellular sampling and sensing, biophysical interaction and bioelectronics.

    • Roey Elnathan
    • Maria Grazia Barbato
    • Ciro Chiappini
    Review Article
  • The introduction of topology into acoustic platforms enables robust sound control. This Review discusses the fundamental mechanisms, basic designs, practical realizations and promising future directions for topological acoustic systems.

    • Haoran Xue
    • Yihao Yang
    • Baile Zhang
    Review Article
  • Data-driven approaches based on high-throughput capabilities and machine learning hold promise in revolutionizing human-centred materials discovery for sustainability and decarbonization. This Review examines the strengths and limitations of different traditional and emerging approaches to demonstrate their inherent connection and highlight the evolving paradigms of materials design.

    • Jiayu Peng
    • Daniel Schwalbe-Koda
    • Yang Shao-Horn

    Collection:

    Review Article
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