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Volume 5 Issue 5, May 2021

A ‘reversible’ catalyst allows a reaction to proceed rapidly even at small departures from equilibrium. These fast and energy-efficient transformations are part of a relatively smooth potential energy landscape that can feature in synthetic and biological systems alike. See Fourmond, Plumeré & Léger.

Image: Laurent Eisler; Design: Carl Conway.

Books & Arts

  • A review of Walter Isaacson’s book The Code Breaker, which takes us behind the scenes to reveal the personal stories of the chemists behind the CRISPR gene editing technology.

    • Kevin Davies
    Books & Arts


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Research Highlights

  • A combined experimental and computational approach provides structural insight into amorphous metal–organic frameworks.

    • Claire Ashworth
    Research Highlight
  • A diversity-oriented synthesis approach to prepare libraries of porous materials has enabled the identification of polymers with specific and tunable lithium-ion transport properties that may be applied in the production of more efficient batteries and fuel cells.

    • Stacey-Lynn Paiva
    Research Highlight
  • Surface tension can help peel a 2D drawing away from the paper and convert it into a 3D object.

    • Gabriella Graziano
    Research Highlight
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  • Developments in synthetic chemistry are increasingly driven by attempts to improve both selectivity and sustainability. This Review highlights the versatility of bifunctional reagents in generating chemical complexity with enhanced atom-economy-leveraging radical reactions, C–H functionalizations, cross-couplings, organocatalysed processes and cyclizations.

    • Huan-Ming Huang
    • Peter Bellotti
    • Frank Glorius
    Review Article
  • Photocatalysis is widely used in numerous fields, including chemistry and biology. This Review highlights the impact of photosensitization and photoredox photocatalysis within therapeutic development, bioconjugation and for probing complex cellular environments.

    • Keun Ah Ryu
    • Christina M. Kaszuba
    • Olugbeminiyi O. Fadeyi
    Review Article
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  • Theoretical models of clusters that account for molecular symmetry offer guidelines for their design. This Perspective describes the models and how we can synthesize the clusters thus designed.

    • Takamasa Tsukamoto
    • Tetsuya Kambe
    • Kimihisa Yamamoto
  • Understanding the relationship between reaction rate and thermodynamic driving force is central to developing efficient catalysts. This Perspective describes this relationship and the conditions that can give rise to reversible catalysis, which is relevant to energy conversions of fuels and motor proteins alike.

    • Vincent Fourmond
    • Nicolas Plumeré
    • Christophe Léger
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Amendments & Corrections

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