Volume 5 Issue 2, February 2021

Bio-othogonal chemistry lets us determine the fate of a lignin monomer using a radical tag and EPR spectroscopy.

An electrosynthetic coupling of olefins with ketones provides an alternative approach to synthesize tertiary alcohols traditionally prepared through Grignard addition to ketones, providing a forward path for an unusual disconnection.

If chemistry is to contribute effectively to the development of a more sustainable world, it is essential that it is taught within a broader socioeconomic and ecological context.

Bispecific antibodies are an up-and-coming type of construct among biologics. They are currently being produced by genetic engineering and expression. This Review highlights recently developed chemical methods for their construction.

DNA is a promising scaffold for guiding biomineralization. This Review describes how DNA nanostructures template calcium-based and silica biominerals, with applications envisioned in biomedicine, electronics and engineering.

Several transition-metal and lanthanide complexes undergo circularly polarized luminescence. This Review describes design principles for the complexes and instruments used to measure them, including in the context of security inks.

Chemical reactions can still occur at temperatures as low as 1 μK. Under such conditions, however, quantum effects are increasingly important, challenging the common understanding of chemical reactivity. The current developments of experimental and theoretical approaches are starting to provide us with a clearer picture of chemistry close to absolute zero.