Volume 1 Issue 7 July 2017

Volume 1 Issue 7

The pore sizes in covalent organic frameworks (COFs) can be tuned by selecting the appropriate building blocks. Applying the mathematical principles of tessellation to the synthesis of 2D COFs will allow the selective preparation of multiporous materials — a key requirement for many potential future applications.

See: Jin, Y., Hu, Y. & Zhang, W. Nat. Rev. Chem. 1, 0056 (2017).

Image and Design: Rachael Tremlett

Research Highlights

Comments and Opinion

  • Comment |

    For long-duration space exploration to be successful, it is essential that chemistry research in space — which has been neglected to date — is intensified. The results of this research is also likely to be of benefit to those at home on Earth.

    • Richard Jones
    • , Ferenc Darvas
    •  & Csaba Janáky

Reviews and Perspectives

  • Perspective |

    Covalent organic frameworks (COFs) have potential applications in, for example, gas storage and separation. The pore sizes in these materials are tunable by selection of the building blocks, and materials with multiple pore sizes are desirable. This Perspective considers synthetic approaches to 2D COFs that rely on tessellation to prepare such multiporous materials.

    • Yinghua Jin
    • , Yiming Hu
    •  & Wei Zhang
  • Review Article |

    Transition metal catalysis is well established as an enabling tool in synthetic organic chemistry. Photoredox catalysis has recently emerged as a method to effect reactions that occur through single-electron-transfer pathways. Here we review the combination of the two to show how this provides access to highly reactive oxidation states of transition metals and distinct activation modes that further enable the synthetic chemist.

    • Jack Twilton
    • , Chi (Chip) Le
    • , Patricia Zhang
    • , Megan H. Shaw
    • , Ryan W. Evans
    •  & David W. C. MacMillan
  • Review Article |

    Enzymes that are optimized for low temperatures have characteristics that are distinct from those that operate under milder conditions. This Review examines cold-adapted enzymes and describes how computational studies have highlighted structural and energetic consequences that arise from adaptation to cold environments.

    • Johan Åqvist
    • , Geir Villy Isaksen
    •  & Bjørn Olav Brandsdal
  • Review Article |

    An untargeted mass spectrometry analysis of a biological sample will detect both biological molecules and compounds that are derived from, for example, diet and the environment. This Review examines the design of such experiments, how to process and interpret the vast amount of data that are produced, and how far we are from being able to use mass spectrometry to inventory the world around us.

    • Alexander A. Aksenov
    • , Ricardo da Silva
    • , Rob Knight
    • , Norberto P. Lopes
    •  & Pieter C. Dorrestein