Volume 1 Issue 2 February 2017

Volume 1 Issue 2

2D allotropes often exhibit peculiar properties. Although graphene — which can be isolated from the naturally occurring layered bulk counterpart, graphite — is the most popular representative of this class of materials, the library of 2D materials is being significantly expanded to elemental species like borophene, silicene and phosphorene that offer unique structures and functions.

Image and design: Rachael Tremlett

Research Highlights

Comments and Opinion

  • In the Classroom |

    Experienced chemists know that chemistry is all around them. Helping students to see the connections between real life and concepts of organic chemistry is the driving force behind the development of a set of online resources pioneered at UCLA.

    • Tejas K. Shah
    •  & Neil K. Garg

Reviews and Perspectives

  • Perspective |

    Recent developments in systems chemistry have shown how the molecular building blocks of life could have arisen from plausible prebiotic feedstocks. This Perspective argues that we remain a long way from a full picture and speculates on what pieces of the puzzle are still missing.

    • John D. Sutherland
  • Review Article |

    This Review covers recent progress and current challenges in the synthesis and stabilization of elemental 2D materials — topical species with peculiar properties. The further development of preparative methodologies will help to expand the 2D materials library well beyond naturally occurring layered materials, and afford products with unique structures and functions.

    • Andrew J. Mannix
    • , Brian Kiraly
    • , Mark C. Hersam
    •  & Nathan P. Guisinger
  • Review Article |

    The primary goal of a process chemist is to develop a commercially viable synthetic route to a known drug candidate. The approaches to a synthetic challenge are consequently very different to those used in medicinal chemistry. This Review uses case studies to highlight important considerations, and the tactics used during the design and selection of an efficient drug synthesis.

    • Martin D. Eastgate
    • , Michael A. Schmidt
    •  & Keith R. Fandrick


  • Review Article |

    Gold surfaces decorated with organosulfur ligands are of nanotechnological importance. Despite this, gold-sulfur interactions — to which van der Waals forces contribute significantly — have only recently been studied in depth. This Review covers these and other soft-soft interactions in which van der Waals forces determine bonding outcomes.

    • Jeffrey R. Reimers
    • , Michael J. Ford
    • , Sebastian M. Marcuccio
    • , Jens Ulstrup
    •  & Noel S. Hush