Biomimetic membranes

Self-assembled lipid membranes are considered an essential cellular subsystem. The synthesis of these membranes is a key step in understanding the transition from non-living chemistry to biology.

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  • The combination of mass spectroscopy-based proteomics with molecular dynamics enables the in-depth study of metallothioneine-Zn(II) binding mechanisms, critical to cell homeostasis and Zn(II) ion buffering.

    • Colette Whitfield
    Research Highlight
  • A geometrically constrained phosphine bearing a tridentate NNS pincer ligand can afford thermoneutral activation of N−H in ammonia.

    • Stacey-Lynn Paiva
    Research Highlight
  • The kinetics of proton-coupled electron transfer during electrocatalytic oxygen reduction are optimized when hydrogen bonding between reaction intermediates and ionic liquids coating the catalyst is maximized.

    • Ronghuan Zhang
    Research Highlight
  • Hydrogen-bonded organic frameworks can be employed to encapsulate protein therapeutics for enhanced cell uptake and intracellular biocatalysis.

    • Colette Whitfield
    Research Highlight
  • Homochiral porous cage-in-cage structures that self-assemble from lanthanide cations and chiral amino acid-derived ligands have been prepared and shown to be highly effective in enantioselective separations of small-molecule guests.

    • Peter W. Seavill
    Research Highlight
  • The supramolecular assembly of oligomers encoded with complementary recognition units enables duplex hybridization with helical structure.

    • Colette Whitfield
    Research Highlight
Nobel Prize in Chemistry 2021

Nobel Prize in Chemistry 2021

The 2021 Nobel Prize in Chemistry has been awarded to Benjamin List and David MacMillan for the development of asymmetric organocatalysis.
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