Volume 2

  • No. 6 June 2024

    High-throughput microfluidic 3D cell culture systems can be designed with different biological complexity, cell sources and cell configurations to model aspects of human tissues and organs. Such microfluidic systems can thereby serve as non-clinical testing tools for drug development. See Jihoon Ko et al.

  • No. 5 May 2024

    Prosthetic embodiment refers to the incorporation of a prosthesis into one’s sensory and functional body schema, requiring the consideration of a user’s sense of agency and ownership. This may be achieved by engineering bionic limbs that leverage a closed-loop mechanoneural-machine interface to allow bidirectional information transfer between the peripheral nervous system and external assistive devices. See Tony Shu et al.

  • No. 4 April 2024

    Bioplastics are derived from renewable carbon sources and/or are degradable at their end-of-life stage, thereby providing a potential solution to plastics pollution. However, lengthy and expensive testing and certification processes, as well as greenwashing and public misconceptions currently hinder the widespread usage and adequate disposal of bioplastics. See Lam Tan Hao et al.

  • No. 3 March 2024

    Nanoparticles can be systemically injected into the body for cancer diagnosis and treatment. Active transport mechanisms may enable nanoparticles to enter the tumour through active endothelial transport processes, retain in the tumour owing to interactions with tumour components, and exit the tumour through lymphatic vessels. See Luan N.M. Nguyen et al.

  • No. 2 February 2024

    Single-cell RNA sequencing techniques and analysis methods can help improve our understanding of tissue injury responses and inform the design of new regenerative biomaterials and therapeutics. See Anna Ruta et al.

  • No. 1 January 2024

    The motions of the heart are regulated by electrophysiological signals, which can be monitored and altered by bioelectronic devices for the diagnosis and treatment of cardiovascular diseases. In particular, soft bioelectronic devices, composed of deformable and conductive materials, can be implanted or designed as wearable devices to enable conformal contact with heart tissue or the skin for real-time and precise diagnosis and treatment. See Sung-Hyuk Sunwoo et al.