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Our May issue

Prosthetic embodiment and mechanoneural-machine interfaces, machine learning for antimicrobial peptide design, biomaterials for adoptive cell therapy, artificial urinary biomarker probes and more

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  • A plate with 3D-printed meat, tomatoes, rice, a glas of milk handed by a robot

    This collection brings together articles discussing the science and societal implications of engineered food, from genome-edited crops and computer-aided food engineering to cellular agriculture, nanotechnology-enabled plant agriculture and agricultural robotics.

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    Nature Reviews Bioengineering is launching a competition asking students and Postdocs around the globe to theoretically tackle some of the most pressing bioengineering challenges. Three challenges are awaiting innovative and creative solutions – from the idea to the sketch of a prototype – take part now!

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  • Organoid intelligence towards biocomputing may provide insights into the neuroscience of learning and memory, and offer a biohybrid form of information processing. Advances in brain region-specific organoid engineering, sensors and signal-processing tools, integration of artificial intelligence, and miniaturization will pave the way for organoid intelligence to make an impact in biomedicine and beyond.

    • Lena Smirnova
    Comment
  • Prosthetic embodiment, or the incorporation of a prosthesis into one’s sensory and functional body schema, may be achieved by engineering bionic limbs that leverage a closed-loop mechanoneural–machine interface. However, the subjective experience of embodiment remains difficult to define and assess.

    Editorial
  • University departments may benefit from guidelines not only to craft effective diversity, equity and inclusion plans, but also to measure progress towards achieving specific goals. This Perspective presents a framework for building, assessing and continuously improving strategic plans to improve recruitment and retention and make departments more inclusive.

    • Jacqueline C. Linnes
    • Erika Moore
    • Rebecca Kuntz Willits
    Perspective
  • Viruses can be engineered to deliver nucleic acids, peptides and proteins for plant trait reprogramming. Building on market approvals and sales of recombinant virus-based biopharmaceuticals for veterinary and human medicine, similar innovations may be applied to agriculture for transient or heritable biodesign of crops with improved performance and sustainable production.

    • Fabio Pasin
    • Mireia Uranga
    • Choon-Tak Kwon
    Comment
  • Artificial intelligence (AI) is finding its way into healthcare. Therefore, medical students need to be trained to be ‘bilingual’ in both medical and computational terminology and concepts to allow them to understand, implement and evaluate AI-related research.

    • Yosra Magdi Mekki
    • Susu M. Zughaier
    Comment
  • Smart food packaging technologies can actualize real-time, in situ food quality monitoring, increasing food safety and decreasing food waste. Here, we detail challenges that hinder the commercialization of such smart packaging systems and identify opportunities to facilitate their translation from prototype to product.

    • Shadman Khan
    • Zeinab Hosseinidoust
    • Tohid F. Didar
    Down to Business
  • The organic electrochemical transistor stands out as a tool for constructing powerful biosensors owing to its high signal transduction ability and adaptability to various geometrical forms. However, the performance of organic electrochemical transistors relies on stable and seamless interfaces with biological systems. This Review examines strategies to improve and optimize interfaces between organic electrochemical transistors and various biological components.

    • Abdulelah Saleh
    • Anil Koklu
    • Sahika Inal
    Review Article
  • Wound healing mechanisms differ depending on the sex, particularly in chronic wounds. Therefore, sex should be considered in the design of nanomedicine- and biomaterials-based wound healing therapies, both in preclinical and clinical testing.

    • Negar Mahmoudi
    • David R. Nisbet
    • Morteza Mahmoudi
    Comment