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Our July issue

Striking the simplicity-complexity balance, soft bioelectronics, hydrogel design, bioelectronic interfaces, organoids integrated with organs-on-chips, nanoscale anisotropy and more

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    Interested in meeting our editors in a virtual lab or site visit? Click the link above to find out more.

  • A plate with 3D-printed meat, tomatoes, rice, a glas of milk handed by a robot

    This collection brings together articles discussing the science and societal implications of engineered food, from genome-edited crops and computer-aided food engineering to cellular agriculture, nanotechnology-enabled plant agriculture and agricultural robotics.

  • Engineering visual

    Nature Reviews Bioengineering is launching a competition asking students and Postdocs around the globe to theoretically tackle some of the most pressing bioengineering challenges. Three challenges are awaiting innovative and creative solutions – from the idea to the sketch of a prototype – take part now!

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  • An article in Science Robotics reports green algae-based microrobots, carrying macrophage membrane-coated nanoparticles, that can be orally administered to neutralize proinflammatory cytokines in the gastrointestinal tract to treat inflammatory bowel disease.

    • Christine-Maria Horejs
    Research Highlight
  • This Review explores the principles and applications of cell purification technologies, with a particular emphasis on their clinical relevance for pluripotent stem-cell-based therapies. The authors discuss current technologies and emerging state-of-the-art approaches that promise even greater potential.

    • Melanie Generali
    • Yoshihiko Fujita
    • Hirohide Saito
    Review Article
  • Degenerative retinal dystrophies, such as retinitis pigmentosa and age-related macular degeneration, lead to blindness owing to the progressive damage of retinal photoreceptors. This Review discusses nanotechnology-based treatment approaches for vision restoration.

    • Guglielmo Lanzani
    • Greta Chiaravalli
    • Fabio Benfenati
    Review Article
  • Nanozymes are nanomaterials that exert biocatalytic functions within biological systems. This Review discusses the design criteria and mechanisms of nanozymes for in vivo applications to treat different pathological disorders.

    • Ruofei Zhang
    • Bing Jiang
    • Xiyun Yan
    Review Article
  • Drug delivery systems can be integrated with cell therapies to improve the efficacy and safety of therapeutic cells. This Review discusses the design of nanoscale, microscale and macroscale drug delivery systems for precise cell modulation, targeted cell and cargo delivery and cell protection.

    • Lily Li-Wen Wang
    • Yongsheng Gao
    • Samir Mitragotri
    Review Article
  • Bioengineering breakthroughs often arise from deceptively simple solutions, leveraging scalability, modularity and ease-of-use. However, certain biomedical applications require the integration of custom-engineered, patient-specific complexity. Striking this simplicity–complexity balance will drive affordable, globalized health innovations.

    Editorial
  • At the Gates Foundation, the newly established Women’s Health Innovations team supports the research, development and increased access to innovative products, devices and platforms aimed at improving women’s health. Importantly, women should have a central role in the women’s health innovation ecosystem, leading research, shaping strategies and making funding decisions.

    • Ru-fong Joanne Cheng
    • Mark A. Barone
    Comment
  • Human brain organoids can partly mimic features of the human brain. This Perspective discusses key ethical considerations in human brain organoid research and introduces an ethical framework of mindful innovation to conceptualize and guide ethical considerations of human brain organoid research.

    • Nathan A. Shlobin
    • Julian Savulescu
    • Matthew L. Baum
    Perspective
  • Insect-derived proteins and fats present viable food constituents. They can be bioengineered and fermented to improve their nutritional value and functionality to promote food security and the development of new superfoods. Nonetheless, scale-up production and translation of insect-derived proteins and fats remain difficult.

    • Seyed Mohammad Taghi Gharibzahedi
    • Zeynep Altintas
    Comment