nanomaterials for the genetic manipulation of plants

Our May issue

Overcoming the language barrier in science communication, plant genetic engineering, electrochemical biosensors, organoid engineering, bioreactors and more.

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  • An article in Nature Biomedical Engineering reports a simple and hardware-independent peptide-mediated delivery method for the CRISPR-mediated engineering of T cells.

    • Nesma El-Sayed Ibrahim
    Research Highlight
  • Animal cells can be cultured in vitro to fabricate meat-like, edible products with the aim to provide a sustainable source of animal protein while improving animal welfare and reducing the environmental impact of meat production. CellX is a China-based startup company that aims to commercialize cultured meat in China.

    • Ning Xiang
    • Ximing Zhang
    Down to Business
  • Renal function can be replaced by bioengineered kidney tissue. This Review discusses in vivo kidney engineering, xenotransplantation, blastocyst complementation and stem-cell-derived kidney tissue engineering as approaches for renal replacement therapy.

    • Melissa H. Little
    • Ton J. Rabelink
    Review Article
  • Scientific knowledge is mostly communicated in English, which may pose a barrier for non-native English speakers in writing and talking about their research. However, scientific communication can be improved by following some simple rules and taking advantage of old and new tools.

    Editorial
  • Continuous monitoring of diverse biomolecular signatures has the potential to transform our understanding of personalized and preventative medicine. This Review Article discusses the emerging trends and pertinent considerations for the development of a new generation of body-based biomolecular sensors for in vivo measurement.

    • Connor D. Flynn
    • Dingran Chang
    • Shana O. Kelley
    Review Article
  • Owing to the high failure rates of the current drug development process, biomedical research is undergoing a paradigm shift towards approaches centred on human disease models. This Review critically discusses translationally relevant examples and defines key milestones for their widespread application.

    • Anna Loewa
    • James J. Feng
    • Sarah Hedtrich
    Review Article
  • Healthcare hackathons can bring patient-users, problem-solvers and external stakeholders together to formulate individual patient-user problems and find innovative solutions. Lessons can be learned from open innovation research to organize hackathons that ultimately lead to the design of new patient-specific products.

    • Chan Hyung Park
    • Georg von Krogh
    • Yash Raj Shrestha
    Comment
  • Peptide epitopes of structural and signalling proteins constitute the language through which cells communicate and orchestrate biological processes. This Review provides a library of peptide epitopes that can serve as a molecular toolbox for the design of bioactive synthetic matrices.

    • Cosimo Ligorio
    • Alvaro Mata
    Review Article