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Blood glucose concentration measurement without finger pricking
A new sensor that detects optoacoustic signals generated by mid-infrared light enables measurement of glucose concentration from intracutaneous tissue rich in blood. This technology does not rely on glucose measurements in interstitial fluid or blood sampling and might yield the next generation of non-invasive glucose-sensing devices for improved diabetes management.
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Systemic proteome adaptions to 7-day complete caloric restriction in humans
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A GIPR antagonist conjugated to GLP-1 analogues promotes weight loss with improved metabolic parameters in preclinical and phase 1 settings
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Metformin and feeding increase levels of the appetite-suppressing metabolite Lac-Phe in humans
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Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia