Fasting proteome

Fasting proteome

  • Maik Pietzner
  • Burulça Uluvar
  • Claudia Langenberg


  • Healthy diet

    The editors at Nature Metabolism, in collaboration with the editors from Nature Communications,npj Metabolic Health and Disease and Scientific Reports invite submissions of original primary research papers that focus on preclinical and clinical (interventional or observational) studies assessing dietary patterns and interventions for improving cardiometabolic health.

    Open for submissions
  • Crossing arrows

    The Career Pathways series features the stories of Nature Metabolism authors and their self-professed journeys to publication as young investigators. This Collection brings together the Career Pathway pieces and the original research published in Nature Metabolism by the authors.

  • science lab

    This Collection highlights best practices in experimental design, analysis, and reporting to support the metabolic research community and increase reproducibility of research in the life sciences

  • Nature Conference announcement

    Nature Metabolism participates in the organization of a Nature Conference on the spatiotemporal regulation of metabolism. Topics covered include regulatory principles of subcellular and organismal metabolism, metabolic responses to lifestyle interventions, as well as metabolic alterations during ageing or cardiometabolic diseases. Join us in Wuhan in June 2024

Nature Metabolism is a Transformative Journal; authors can publish using the traditional publishing route OR via immediate gold Open Access.

Our Open Access option complies with funder and institutional requirements.


  • As a counterpoint to the increasing complexity and amount of data in manuscripts, we introduce Brief Communications as our shortest article type yet.

  • Recent technological advances permit the profiling of metabolic changes in single cells, which sheds light on how metabolism regulates immune responses. We advocate for accessible and standardized tools to reduce the barrier of entry to immunometabolism studies and facilitate the translation of fundamental findings towards clinical applications.

    • Jason Cosgrove
    • Antoine Marçais
    • Jan Van den Bossche
  • When preparing your manuscript, clear presentation of the data and concise writing are key. In this Editorial, we offer tips on how to better communicate your results.

  • Non-alcoholic liver disease (NAFLD) is now metabolic dysfunction-associated steatotic liver disease (MASLD), emphasizing the key metabolic factors of obesity, insulin resistance, vascular dysfunction and dyslipidaemia. Here, we discuss impacts on the existing body of clinical and preclinical liver disease research and on research moving forward.

    • Cynthia L. Hsu
    • Rohit Loomba
  • The prevailing notion that mitochondrial diseases arise from ATP deficiency is challenged by recent evidence that oxidative phosphorylation defects trigger maladaptive stress responses consuming excess energy. We argue that this chronic state of hypermetabolism imposes energetic constraints, thus causing mitochondrial disease pathophysiology, calling for careful translational studies from organelle to organism.

    • Alexander J. Sercel
    • Gabriel Sturm
    • Martin Picard