Volume 2 Issue 5, May 2024

Increasing inequality and social fragmentation may give rise to a collective state of despair that may not only diminish the desire to live but also dampen the drive to reproduce, resulting in shrinking fertility and population decline.

The COVID-19 pandemic has caused profound mental health problems among left-behind children (LBC). Here we discuss the challenges that LBC are facing in the post-COVID-19 era and the potential underlying mechanisms, and provide recommendations for future policy priorities.

In this Perspective, authors argue for a more robust and comprehensive postmarket surveillance program of psychedelic-assisted psychotherapy to better ensure safe, appropriate and equitable care for patients.

In this Perspective, the authors make recommendations on better aligning stakeholders, including those in technology, practitioners and researchers, to increase collaboration and governance in technology and mental health.

This Review discusses the specific challenges and strategies in supporting individuals with ADHD during the critical transition to adulthood and outlines arguments for engaging and training parents.

In this Review, the authors discuss the neurobiological mechanisms of motor cortex-related analgesia, drawing insights from both experimental data and clinical data.

Using a longitudinal structural imaging design, the authors assessed cortical anatomy and genes linked to methylphenidate activity to identify treatment-associated responses in adults with attention deficit hyperactivity disorder.

The authors examine the longitudinal relationship between residential greenness and the incidence of depression and anxiety using a sample of 409,556 participants from the UK Biobank.

Using a large sample from the UK Biobank, the authors investigate the effects of dietary patterns on multiple aspects of brain health and mental health.

A study on a large cohort of military veterans of European and African ancestries finds no evidence that the APOE ε4 genotype moderates the impact of combat exposure on posttraumatic stress disorder symptom severity and diagnostic status.

In this article, the authors demonstrate that haloperidol D2/D3 dopamine antagonism contributes to flexibility in beliefs about the intentions of social partners during a sharing game.

Singh and colleagues present an integrative genotypic approach using large-scale GWAS data for depression and coronary artery disease to identify genes associated with both conditions.

Using stereotactic electroencephalography, the authors identified differential amygdala activation in response to emotional faces in participants with treatment-resistant depression compared with non-depressed participants with epilepsy, suggesting possible deep brain stimulation targets.

In this cross-species translational study, the authors look at the longitudinal consequences of stress during adolescent development on HPA function and postpartum behaviors in mice and in humans and suggest that glucocorticoid receptor antagonists may serve as a potential treatment for postpartum depression.

This study identifies a set of risk factors that fully mediate and uniquely contribute to the relationship between sex assigned at birth and posttraumatic stress disorder severity.

The authors conducted a systematic review to examine whether pharmacogenetic testing affects clinical or economic outcomes in patients taking antipsychotic medication.