Using a sample of more than 1 million individuals, Hatoum et al. identify genomic loci associated with general and substance-specific addiction risk.

Panayiotou et al. performed a panel network analysis to investigate the relationship between time spent on social media and mental health in a large cohort of UK adolescents.

Galante et al. performed a systematic review and meta-analysis using individual participant data from randomized controlled trials evaluating mindfulness-based programs for adult mental health promotion in non-clinical settings.

Catarino et al. used real-world data from the UK healthcare system to perform an economic evaluation comparing the cost-effectiveness of in-person and internet-delivered cognitive behavioral therapy for mood and anxiety disorders.

Chiba & Ide et al. used the data from a Japanese longitudinal cohort study to investigate the suicide risk in the general population before and after the COVID-19 pandemic.

Nicotine withdrawal and anxiety symptoms are overlapping barriers to smoking cessation. We examined the effects of a smoking cessation treatment — noninvasive neuromodulation — on nicotine withdrawal and anxiety symptoms, which revealed information on how neuromodulation can treat substance use disorders.

Short-lived online social network experiments show that making the in-game wealth of immediate neighbors invisible improves the subjective wellbeing (SWB) of poorer participants. This status invisibility reduced the strength of the positive association between in-game wealth and SWB in social networks. However, in real-world settings, status is often visible.

In this Perspective the authors detail the potentially parallel systemic economic risk of psychological distress and climate change, and argue for the adoption of a similar set of policy interventions, including bolstering cross-agency capability and capacity and increased investment in targeting root causes and solutions.

A neuroimaging study using repeated transcranial magnetic stimulation on unmedicated patients with depression reveals a link between response in the subgenual anterior cingulate cortex and clinical improvement.

Using two series of online experiments involving a public goods game and manipulation of wealth visibility, the authors show that invisible wealth achieved higher subjective well-being, particularly among poorer subjects leading to a reduction in the economic gradient in well-being.

In this Q&A, we speak to David Furman, the director of the Stanford 1000 Immunomes Project and chief of the Center for Artificial Intelligence and Data Science of Aging at the Buck Institute for Research on Aging. His research aims to better understand the aging of the immune system and improve the health and lives of many people.

In this randomized, crossover study, the authors applied high-frequency repetitive transcranial magnetic stimulation to the dorsolateral prefrontal cortex or to the visual cortex (V5) on patients with tobacco use disorder to elucidate the underlying cognitive and affective mechanisms of repetitive transcranial magnetic stimulation for smoking cessation.

Voetterl and colleagues examined the application of ‘Brainmarker-I’, an age- and sex-normalized electroencephalogram measure of individual alpha peak frequency, on predicting remission to therapeutic noninvasive neuromodulation protocols (repetitive transcranial magnetic stimulation and electroconvulsive therapy).