As many authors are experimenting with using large language models in writing articles, some guidelines are becoming clear, but these will need to evolve as the capabilities and integration of such tools develop further.

There are numerous algorithms for generating Shapley value explanations. The authors provide a comprehensive survey of Shapley value feature attribution algorithms by disentangling and clarifying the fundamental challenges underlying their computation.

Generative AI programs can produce high-quality written and visual content that may be used for good or ill. We argue that a credit–blame asymmetry arises for assigning responsibility for these outputs and discuss urgent ethical and policy implications focused on large-scale language models.

Deep learning can be used to predict molecular properties, but such methods usually need a large amount of data and are hard to generalize to different chemical spaces. To provide a useful primer for deep learning models models, Fang and colleagues use contrastive learning and a knowledge graph based on the Periodic Table and Wikipedia pages on chemical functional groups.

Designing methods to induce explicit and deep structural constraints in latent space at the sample level is an open problem in natural language processing-derived methods relying on transfer learning. McDermott and colleagues propose and analyse a pre-training framework imposing such structural constraints, and empirically demonstrate its advantages by showing that it outperforms existing pre-training state-of-the-art methods.

While single-cell multimodal datasets allow for the measurement of individual cells to understand cellular and molecular mechanisms, generating multimodal data for many cells is costly and challenging. Cohen Kalafut and colleagues develop a machine learning model capable of imputing single-cell modalities and prioritizing multimodal features, such as gene expression, chromatin accessibility and electrophysiology.

Immersive virtual reality requires artificial sensory perceptions to simulate what we feel and how we interact in the natural environment. Zhang and colleagues present a first-person, human-triggered, active haptic device that allows users to experience mechanical touching with various stiffness perceptions from positive to negative ranges, achieved by the unique benefits of curved origami.

Memory efficient online training of recurrent spiking neural networks without compromising accuracy is an open challenge in neuromorphic computing. Yin and colleagues demonstrate that training a recurrent neural network consisting of so-called liquid time-constant spiking neurons using an algorithm called Forward-Propagation Through Time allows for online learning and state-of-the-art performance at a reduced computational cost compared with existing approaches.

To detect phenotype-related cell subpopulations from single-cell data, appropriate feature sets need to be chosen or learned simultaneously. Ren et al. present here a tool based on Learning with Rejection, a method that during training learns features from cells that can be predicted with high confidence, while cells that the model is not yet certain about are rejected.

Particle tracking velocimetry to estimate particle displacements in fluid flows in complex experimental scenarios is a challenging task and often comes with high computational cost. Liang and colleagues propose a graph neural network and optimal transport-based algorithm that can greatly improve the accuracy of existing tracking algorithms in real-world applications.

The organizers of the TinyML Design Contest describe the top machine-learning-based real-time detection algorithms for ventricular arrhythmia.

As many authors are experimenting with using large language models in writing articles, some guidelines are becoming clear, but these will need to evolve as the capabilities and integration of such tools develop further.

Metaverse-enabled healthcare is no longer hypothetical. Developers must now contend with ethical, legal and social hazards if they are to overcome the systematic inefficiencies and inequities that exist for patients who seek care in the real world.

Generative AI programs can produce high-quality written and visual content that may be used for good or ill. We argue that a credit–blame asymmetry arises for assigning responsibility for these outputs and discuss urgent ethical and policy implications focused on large-scale language models.

Fairness approaches in machine learning should involve more than an assessment of performance metrics across groups. Shifting the focus away from model metrics, we reframe fairness through the lens of intersectionality, a Black feminist theoretical framework that contextualizes individuals in interacting systems of power and oppression.

We are trying to keep up with the torrent of developments and discussions in AI and language models since ChatGPT was unleashed on the world.