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Volume 3 Issue 3, March 2022

Antimicrobial resistance in livestock systems

Antimicrobial use and overuse in livestock production is a key driver of global antimicrobial resistance (AMR) development. Although different antimicrobials are typically used in humans and animals, resistance genes can spread horizontally in the environment — even to bacterial populations with no previous exposure to antimicrobials.

Now, a genomic analysis of Escherichia coli samples taken during the past 50 years from livestock production sites in China reveals patterns of AMR spread and identifies plasmids that conferred increasing resistance for critically important veterinary and human antimicrobials. Policy actions informed by the biology underlying AMR are urgently needed to curtail the use of antimicrobials in livestock production and limit the global spread of AMR.

See Yang et al.

Image: Ted Horowitz / The Image Bank / Getty. Cover Design: Tulsi Voralia.

Correspondence

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Comment & Opinion

  • Effective interfaces of knowledge and policy are critical for food system transformation. Here, an expert group assembled to explore research needs towards a safe and just food system put forward principles to guide relations between society, science, knowledge, policy and politics.

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    • Fabrice DeClerck
    • Gianluca Brunori
    Comment
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Research Highlights

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News & Views

  • An analysis of historical Escherichia coli samples from livestock reveals how antimicrobial resistance can spread — and how understanding the biology underlying its spread can inform effective policy actions.

    • Claire Heffernan
    News & Views
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Research

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