Nature Computational Science is a Transformative Journal; authors can publish using the traditional publishing route OR via immediate gold Open Access.

Our Open Access option complies with funder and institutional requirements.


  • An analysis of GPS pedestrian traces shows that (1) people increasingly deviate from the shortest path when the distance between origin and destination increases and that (2) chosen paths are statistically different when origin and destination are swapped. Ultimately, this can explain the observed human attitude in selecting different paths upon return trips.

    • Christian Bongiorno
    • Yulun Zhou
    • Carlo Ratti
  • An algorithmic approach is developed to analyze large-scale patient safety data and remove the confounders of reporting trajectory and drug inference. Such an approach can be effectively used to investigate demographic disparities of drug safety and to identify at-risk patients during a pandemic.

    • Xiang Zhang
    • Marissa Sumathipala
    • Marinka Zitnik
    Article Open Access
  • The authors show that accurate bootstrap confidence limits on inferred evolutionary relationships of species can be estimated by bootstrapping a collection of little samples of very long sequence alignments. Little bootstraps take a fraction of computer time and memory compared to the standard bootstrap, enabling big data analytics on personal computers.

    • Sudip Sharma
    • Sudhir Kumar
    Brief Communication