Stability is a key property for any catalyst. The description of stability, however, varies in the literature depending on the subfield. In this Review the authors present a systematic literature analysis aimed at identifying generalized deactivation modes and their prevalence in different areas of catalysis to offer a comprehensive descriptive framework of catalyst deactivation.

Metabolic engineering of microbes constitutes a promising strategy to make the industrial production of chemicals more sustainable. This Review discusses recent advances of targeted high-throughput genome editing to construct next-generation cell factories for bioproduction.

Single-atom, small cluster and nanoparticle catalysts feature intriguing reactivity for a variety of transformations, which is often attributed to the properties of specific atomic species. This Review critically revisits the reactivity of such catalysts in term of the ensemble effects that arise from the interaction of multiple metal atoms or single atomic species with neighbouring atoms from supports, additives or surface ligands.

The 27th United Nations Climate Change Conference placed the risks of greenwashing under the spotlight. In this Editorial, we reflect on the implications of this phenomenon for science and peer review.

Organic semiconductors have potential for application as photocatalysts, but their efficiency is limited by recombination of charge carriers before they can reach the surface. Here hydrogen-bonded organic frameworks with designed micropores decrease the exciton transfer path to improve charge utilization in photocatalytic H₂ evolution.

CO₂ methanation offers a route to synthetic methane production but typically requires high temperatures to achieve sufficient rates. This study presents light-driven CO₂ methanation on an Au/Ce_0.95Ru_0.05O₂ solid-solution catalyst with high CH₄ production rate and selectivity benefiting from synergistic photochemical and photothermal effects.

While hydrosulfenation via addition of sulfenic acid to alkynes was reported decades ago, an asymmetric version of this reaction remained elusive. Now, Ni-catalysed hydrosulfenation of alkynes with in situ-generated sulfenic acids enables the synthesis of chiral alkenyl sulfoxides.

Molecular insights into the mechanism of amide bond formation in the biosynthesis of lincosamide antibiotics remain scarce. Now, the crystal structure of the condensation enzyme CcbD that catalyses this reaction is solved, its substrate scope investigated and a catalytic mechanism proposed.

Supported subnanometric clusters are a much sought-after class of catalyst, but governing the anchoring onto the support and the resulting properties of the clusters remains a challenge. Now the authors show how UTL-type germanosilicate can stabilize ultra-fine Pt clusters, resulting in a superior catalyst for propane dehydrogenation.

Shuttle catalysis is a promising approach to improve traditional hydrofunctionalization reactions, although thermodynamic constraints limit its application. Here the authors show how the properties of zeolites can drive the shuttling equilibrium of such catalytic processes, widening the applicability of reactions such as transfer hydrocyanation and transfer hydroformylation.